1974
DOI: 10.1001/archpedi.1974.02110270025006
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Cerebrospinal Fluid Lactic Acid Level and pH in Meningitis

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Cited by 93 publications
(31 citation statements)
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“…High concentrations of CSF lactate have been found in patients with BM despite a low neutrophil count [32]. This clinical observation has also been made in experimental BM where high levels of CSF lactate were documented in neutropenic and normal control animals, independent of the presence of neutrophils in CSF [21].…”
Section: Discussionsupporting
confidence: 53%
“…High concentrations of CSF lactate have been found in patients with BM despite a low neutrophil count [32]. This clinical observation has also been made in experimental BM where high levels of CSF lactate were documented in neutropenic and normal control animals, independent of the presence of neutrophils in CSF [21].…”
Section: Discussionsupporting
confidence: 53%
“…The cerebrospinal fluid (CSF) plays a major role in the evaluation of the natural history, in the diagnosis and in the follow-up of the infectious and inflammatory pathologies of the CNS [1][2][3] . In many cases, the routine evaluation of the CSF is not sufficient for diagnosing the type of meningitis [4][5][6] .…”
mentioning
confidence: 99%
“…The lactic acid levels in all nine patients with aseptic meningitis were slightly above the uninfected controls; (22.6±6.1 mg/dl) but was not diagnostic. The lactic acid levels remained higher than normal for at least 3 meningitis. In addition to lactic acid and succinic acid, four other minor unidentified peaks were also found, but they were not considered diagnostic.…”
Section: Methodsmentioning
confidence: 88%
“…Lactic acid levels in CSF are increased in cases of purulent bacterial meningitis (3)(4)(5). Leukocyte lactate dehydrogenase activity (6,7) and lysozyme levels increase in bacterial, but not in viral meningitis (8)(9)(10).…”
mentioning
confidence: 99%