Cerebrospinal fluid cytology: Selected issues

Walts, Ann E.

doi:10.1002/dc.2840080420

Cited by 13 publications

(7 citation statements)

References 105 publications

(29 reference statements)

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“…45 There can be a marked lymphocytic or monocytic pleocytosis, in which case organisms are hard to identify. 45 There can be a marked lymphocytic or monocytic pleocytosis, in which case organisms are hard to identify.…”

Section: Cryptococcal Meningitismentioning

confidence: 99%

Cerebrospinal Fluid

Cibas¹

2009

Cytology

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Section: Cryptococcal Meningitismentioning

confidence: 99%

Cerebrospinal Fluid

Cibas¹

2009

Cytology

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“…Rearrangement of the DNA encoding for the antigen-receptor occurs as a normal event in the maturation of T-and B-lymphocytes; its presence in a population of lymphocytes suggests that those cells belong to a single clone and are usually neoplastic in origin. Although it has been shown that some lymphomas lack detectable clonal gene rearrangements and some benign disorders contain clonal lymphocytic proliferations, these are the exception rather than the rule (Alts, 1992;Tani er al., 1995).…”

Section: Rmsf-rocky Mountain Spotted Fiver; Cll-chronic Lyrnphocytic mentioning

confidence: 99%

Infectious meningitis with atypical cerebrospinal fluid cells

García-Moncó

Beldarrain

Zabalza

1997

Euro J of Neurology

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Cytologic evaluation of the CSF is often difficult when trying to distinguish between truly neoplastic and reactive cells. Several non-neoplastic conditions may be associated with atypical cells in the CSF, a fact the clinician has to consider to avoid inadequate aggressive theraphies. We report here three patients with infectious meningitis (due to Herpes zoster virus in two, and neuroborreliosis in one) and cytologically atypical cerebrospinal fluid lymphocytes. Further characterization showed that the pleocyrosis in these patients was of reactive origin. Cytomorphology is frequently insufficient and histochemical, immuncytochemical and cellular genome analysis techniques may help differentiate atypical reactive cells from neoplastic cells.

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“…Reactive and infective lymphoid infiltrates are polyclonal and include mixed B and T cells, S~~~~~~A L identified by immunocytochemical staining of spare cytospin preparations. 9 A summary of the CSF findings in infective and inflammatory conditions is shown in the table.…”

Section: Chronic Infiammatory Infiltratementioning

confidence: 99%

Update on central nervous system cytopathology. I. Cerebrospinal fluid.

Bell

1994

J Clin Pathol

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Cerebrospinal fluid cytology: Selected issues

Cited by 13 publications

References 105 publications

Cerebrospinal Fluid

Cerebrospinal Fluid

Infectious meningitis with atypical cerebrospinal fluid cells

Update on central nervous system cytopathology. I. Cerebrospinal fluid.

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