Cerebrospinal fluid and its physiology

May, Rosie; Reddy, Ugan

doi:10.1016/j.mpaic.2019.10.017

Cited by 3 publications

(2 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is mainly produced by the epithelium of the choroid plexuses, located in the lumen of the lateral ventricles and in the fourth ventricle. After circulating through the ventricular system, subarachnoid spaces, and ependymal canal, CSF is absorbed into the venous system by the arachnoid granulations ( 4 , 5 ) . Additional sites of absorption include the spinal arachnoid villi near the epidural spinal veins and the meningeal sheaths of the spinal and cranial nerves.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cine phase-contrast magnetic resonance imaging evaluation of cerebrospinal fluid flow dynamics in healthy pediatric subjects

2022

View full text Add to dashboard Cite

Objective: To evaluate cerebrospinal fluid dynamics, using cine phase-contrast magnetic resonance imaging (cine-PC MRI), in healthy pediatric subjects, determining the normal flow values in this population, as well as identifying differences related to age, sex, and body surface area. Materials and Methods: This was a descriptive cross-sectional study involving 32 healthy children and adolescents, in whom the flow of cerebrospinal fluid through the cerebral aqueduct was evaluated quantitatively with cine-PC MRI. We used specialized software to analyze the images obtained with cine-PC MRI, drawing a region of interest on the aqueduct. A flow-time curve was obtained, as were automated measurements of the various parameters. Results: The following normal (mean) values were obtained: net flow, 1.10 ± 0.99 mL/m; stroke volume, 12.2 ± 10.1 μL/cycle; mean velocity, 0.72 ± 1.00 cm/s; peak systolic velocity, 5.28 ± 2.30 cm/s; peak diastolic velocity, 4.51 ± 1.77 cm/s. These values were not affected by age or sex. In addition, body surface area was not found to correlate significantly with mean velocity or stroke volume. Conclusion: In children and adolescents, the basic cerebrospinal fluid flow parameters, as determined by cine-PC MRI, appear to be independent of age and sex.

show abstract

Section: Introductionmentioning

confidence: 99%

“…ventricular system, subarachnoid spaces, and ependymal canal, CSF is absorbed into the venous system by the arachnoid granulations (4,5) . Additional sites of absorption include the spinal arachnoid villi near the epidural spinal veins and the meningeal sheaths of the spinal and cranial nerves.…”

mentioning

confidence: 99%