Cerebrocardial syndrome is a complex of cardiac disorders that occur against the background of damage to the central nervous system and most often develop as a result of cerebral stroke. The article presents a description of a clinical case of cerebrocardial syndrome in a patient with ischemic stroke, the results of diagnostic measures, the dynamics of the electrocardiogram. The clinical significance of cerebrocardial syndrome is that it can cause diagnostic errors and overdiagnosis of cardiac pathology in situations where it does not exist, and, accordingly, lead to improper treatment. An individual approach to the assessment of cardiac disorders in patients with cerebral stroke and regular changes in the neuroendocrine, immune systems, hemostasis system will provide for a timely diagnosis of cerebrocardial syndrome, optimization of treatment and improved prognosis.