Cerebral Venous Sinus Thrombosis Involving the Straight Sinus May Result in Infarction and/or Hemorrhage

Abstract

Aim: We retrospectively investigated the clinical profiles and neuroimaging data of patients with documented cerebral venous sinus thrombosis (CVST) to analyze the relationship between the sites of CVST and clinical manifestations. Methods: A total of 68 patients, who were examined and treated at our hospital, were identified after review and their data were retrospectively analyzed. Results: Initial non-contrast CT scan showed a definite spontaneous hyperdensity of one or several sinuses in 47 patients (69.1%) and was normal in the remaining patients (30.9%). Furthermore, the χ² test revealed a significant difference (p = 0.001) in the infarction or hemorrhage rate between the patients with straight sinus thrombosis (SST; 19 of 28, 67.8%) and other subjects (9 of 39, 23.1%). Moreover, patients with SST had a 6.33-fold (95% CI 2.18-18.4) increased risk of infarction or hemorrhage. Conclusion: Our data suggested that infarction and/or hemorrhage was more common in CVST patients with SST.

Oral contraceptives caused venous sinus thrombosis complicated with cerebral artery infarction and secondary epileptic seizures

“…It was often seen in clinical reports that venous sinus thrombosis leads to thalamus infarcts or venous sinus thrombosis associated with hemorrhage after infarction. [ 2 ] However, venous sinus thrombosis complicated with cerebral artery infarction and secondary epileptic seizures has not been reported. In addition, oral contraceptive has been widely known as a risk factor for CVT.…”

Cerebral venous sinus thrombosis complicated with haemorrhagic venous infarction and seizures, successfully treated with oral anticoagulation for one year: a case report

“…Screening for Systemic Lupus Erythematosus and the antiphospholipid syndrome were also negative. COCP has been widely known as a risk factor for CVST [8][9][10]. In this background, the diagnosis of cerebral venous sinus thrombosis secondary to the oral contraceptive pill was made.…”

An Illustrative Case of Vein of Labbe Thrombosis Presented as a Glioma

“… 1 2 3 CVT is caused by several factors, including infections, genetic thrombophilia, trauma, surgery, dehydration, pregnancy, and oral contraceptives. 4 5 However, the combination of a low incidence rate, non-specific clinical presentations, and atypical magnetic resonance imaging (MRI) has resulted in high misdiagnosis rates of CVT. 6 Our goal is to present the unique case of a young patient whose MRI scan revealed an abnormally enhancing tumor-like brain lesion that was heterogeneous in intensity and whose intraoperative view and histopathological findings were consistent with the vein of Labbe thrombosis (VLT), with ipsilateral transverse and sigmoid sinus involvement.…”