Cerebral venous sinus thrombosis in pregnancy presenting with hemiplegia: A case report

Mahmoud, A.; Ekin, Utku; Kania, Brooke; Shrouf, Ahmad; Maroules, Michael

doi:10.1016/j.radcr.2022.07.006

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…One patient experienced an extensive cerebral infarct with a haemorrhagic transformation and a possible arterial obstruction, while the other had an infarct due to cerebral venous thrombosis associated with positive antinuclear antibodies and prothrombin heterozygous mutation [30]. The experience is increasing with another recent case report of a 22-year-old woman in early pregnancy (10 gestational weeks) presenting with headache and focal neurological deficit, but with a good functional outcome [31]. There is also only one case report at the moment (September 2022) of a spontaneous intracerebral haemorrhage (ICH) associated with pregnancy and COVID-19 so this complication appears to be quite rare [32].…”

Section: Covid-19mentioning

confidence: 99%

Stroke in Pregnancy and Puerperium - Current Knowledge, Questions and Controversies

Pavlović¹

2023

Arch. Psychiatry Res.

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Stroke associated with pregnancy and the postpartum period (SiPP) is not common but its consequences can be devastating both for the mother and the child. Pregnancy confers a substantially increased risk of stroke, especially during the third trimester and until 6 weeks postpartum. SiPP is heterogeneous both in aetiology and presentation as it includes both ischemic and haemorrhagic events as well as cerebral venous thrombosis. Specific risk factors for SiPP have been identified and well described, such as hypertensive disorders of pregnancy and a prothrombotic state. However, it is still a controversial issue if pregnancy should be considered a risk factor for stroke, although pregnancy and postpartum period clearly increase the stroke risk compared to non-pregnant time. Recent European Stroke Organization [ESO] guidelines addressed the management of acute SiPP while other issues, particularly primary and secondary prevention are still under investigated. There is also a lack of research and knowledge regarding long-term mother and foetus/child outcomes post-SiPP. This paper addresses current knowledge on SiPP management and prognosis and discusses new challenging clinical scenarios including the relationship between COVID-19 infection and SiPP.

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Section: Covid-19mentioning

confidence: 99%

Stroke in Pregnancy and Puerperium - Current Knowledge, Questions and Controversies

Pavlović¹

2023

Arch. Psychiatry Res.

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“… 8 One of these factors is an imbalance in the hemostatic system, which is responsible for maintaining the balance between clotting and fibrinolysis. 2 , 9 In this system, a balance between the production of clotting factors and plasminogen activator inhibitors (PAIs) is essential to prevent clot formation. 10 However, during the perinatal state, there is an increase in the production of clotting factors, such as Factor VIII, fibrinogen, and von Willebrand factor, which can lead to an imbalance in the hemostatic system and predispose to the formation of clots in the cerebral venous sinuses.…”

Section: Introductionmentioning

confidence: 99%

Clinical Values of Coagulation Factors X, XI, and XII in Cerebral Venous Sinus Thrombosis During Perinatal State

Li,

Duan,

et al. 2023

Clin Appl Thromb Hemost

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Cerebral venous sinus thrombosis (CVST) has become a rare but potentially life-threatening condition in perinatal women. Early and rapid identification of CVST in pregnant women is a challenge for frontline clinical workers. In this study, 40 perinatal patients with CVST in our hospital were included in the five-year period, and 120 normal perinatal pregnant women in the obstetrics and gynecology department of our hospital were randomly enrolled in the five-year period as the control group, including 60 cases in pregnancy and puerperium. 5 mL of fasting venous blood was collected from puerperal CVST patients in the acute phase of onset (within 72 h of onset) and the recovery phase (fourth week of treatment). In the control group, 5 mL of fasting venous blood was collected. Coagulation factors X, XI, and XII, plasma D-Dimer were analyzed and compared. Coagulation factors X, XI, and XII in plasma of CVST patients were significantly increased compared with controls. Plasma coagulation factors X, XI, and XII and their combined detection (Union Model = 0.056 * FX: C + 0.046 * FXI: C + 0.081 * FXII: C) have diagnostic values for perinatal CVST. Plasma coagulation factors X, XI, and XII were significantly positively correlated with plasma D-dimer levels in perinatal CVST patients. Plasma coagulation factors X, XI, and XII have diagnostic values for perinatal CVST.

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Cerebral venous sinus thrombosis with hemorrhagic infarct: A rare presentation in a risk-defying male patient

Katwal,

Suwal,

Lamichhane

et al. 2024

Radiology Case Reports

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Cerebral venous sinus thrombosis in pregnancy presenting with hemiplegia: A case report

Cited by 4 publications

References 12 publications

Stroke in Pregnancy and Puerperium - Current Knowledge, Questions and Controversies

Stroke in Pregnancy and Puerperium - Current Knowledge, Questions and Controversies

Clinical Values of Coagulation Factors X, XI, and XII in Cerebral Venous Sinus Thrombosis During Perinatal State

Cerebral venous sinus thrombosis with hemorrhagic infarct: A rare presentation in a risk-defying male patient

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