Cerebral sparganosis in mainland Chinese patients

Hong, Daojun; Xie, Hua; Zhu, Min; Wan, Hui; Xu, Renshi; Wu, Yuchen

doi:10.1016/j.jocn.2012.12.018

Cited by 33 publications

(50 citation statements)

References 19 publications

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“…Sparganosis can migrate to various tissues and organs, such as subcutaneous connective tissue, muscle, breast, lungs and the central nervous system [2] . Reported cerebral sparganosis cases are quite small compared to other site sparganosis, but according to Hong et al [18] the prevalence of cerebral sparganosis was underestimated, many cases were not reported. In addition, a lot of Asian patients were reported with local language rather than English.…”

Section: Epidemiologymentioning

confidence: 98%

“…Due to the small wounds, stereotactic aspiration is recommended by most neurosurgeons. In the 26 cerebral sparganosis cases of Hong et al [18] , 16 of them were treated with craniotomy, 7 of them were treated with stereotactic aspiration and another 3 were treated with praziquantel only. None of them experienced a relapse of the disease.…”

Section: Surgerymentioning

confidence: 99%

“…Fever is not a common symptom. Lesions are mainly located at frontal-partial lobes but invasion to cerebellums are also reported in very few cases [18] . Diagnosis of cerebral sparganosis is relatively hard since it has no specific manifestations.…”

Section: Clinical Characteristicsmentioning

confidence: 99%

“…The disease can also be diagnosed with antigen specified IgG antibodies from blood and CSF samples, although cross-reactivity with other infestations or clonorchiasis limititsspecificity [13,18] . In our case, the first CSF sample was negative for immune-reactivity but positive for blood sample, however, the second blood and CSF sample were both positive.…”

Section: Laboratory Test and Neuroimagingmentioning

confidence: 99%

“…Yu et al [13] reported in 8 of 9 cases of cerebral sparganosis patients underwent a craniotomy due to lack of stereotactic equipment, with 1 patient dying due to unspecified reason. Both investigators reported that symptom duration more than one year indicated worse prognosisafter surgery [13,18] . In our case, we used a navigation guided craniotomy to resect the granuloma as well as the peri-lesion glia proliferation zone.…”

Section: Surgerymentioning

confidence: 99%

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Sparganosis of the brain: a case report and brief review

Li¹,

Luan²,

Guo³

et al. 2017

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Section: Epidemiologymentioning

confidence: 98%

Section: Surgerymentioning

confidence: 99%

Section: Clinical Characteristicsmentioning

confidence: 99%

Section: Laboratory Test and Neuroimagingmentioning

confidence: 99%

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confidence: 99%

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Sparganosis of the brain: a case report and brief review

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Luan²,

Guo³

et al. 2017

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Helminth Infections of the CNS

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et al. 2020

Infections of the Central Nervous System

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Cerebral sparganosis: case report and review of the European cases

et al. 2015

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Sparganosis is a severe parasitic infection caused by the larvae of Spirometra mansoni, also called "sparganum." In human hosts, the Spirometra mansoni larva commonly targets the subcutaneous tissue or muscle. Sometimes it can also migrate into the brain, resulting in cerebral sparganosis, mainly characterized by focal neurological symptoms such as seizures and radiological "wandering lesions" on magnetic resonance images (MRIs). Clinical cases of cerebral sparganosis have been reported worldwide, mainly in Asian countries, but also in North America, South America and Australia. Only two cases have been previously reported in Europe. A 29-year-old male from Bolivia, who lived in Spain, presented to our service for seizures and a multicystic brain lesion, initially suspected to be a dysembryoplastic neuroepithelial tumor (DNET). He underwent gross total resection of the mixed solid/cystic lesion. Pathology revealed gliosis, multiple interconnected cystic cavities with fibrous walls, inflammatory cell infiltration and no necrotizing granulomatous reaction. Inside the cavities, a parasitic form was identified as the larva of the cestode Spirometra mansoni. At 1-year follow-up, the patient had no deficits and was seizure free. Clinicians should be alerted to the possible existence of this rare entity in Europe, especially in patients from endemic areas with a possible infection history as well as "wandering lesions" on the MRI.

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Cerebral sparganosis in mainland Chinese patients

Cited by 33 publications

References 19 publications

Sparganosis of the brain: a case report and brief review

Sparganosis of the brain: a case report and brief review

Helminth Infections of the CNS

Cerebral sparganosis: case report and review of the European cases

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