Cerebral palsy in Al-Quseir City, Egypt: prevalence, subtypes, and risk factors

Abstract

Cerebral palsy (CP) is the most frequent cause of motor handicap. The present door-to-door survey was conducted in Al-Quseir City, Egypt, to investigate the epidemiology of CP. All inhabitants were screened by three neurologists. Medical and neurological examinations were performed for all residents and suspected cases of CP were confirmed by meticulous neurological assessment, brain magnetic resonance imaging, electroencephalography, and testing with the Stanford-Binet Intelligence Scale. Forty-six of 12,788 children aged ≤18 years were found to have CP, yielding a childhood prevalence of 3.6 (95% confidence interval 1.48–2.59) per 1,000 live births. Five adults (aged 19–40 years) among 13,056 inhabitants had CP, giving an adult prevalence of 0.4 (95% confidence interval 0.04–0.72) per 1,000. The risk factors for CP identified in this study were premature birth, low birth weight, neonatal jaundice, neonatal seizures, and recurrent abortion in mothers of children with CP.

Establish Registry of Cerebral Palsy in Tanta Egypt

“…In our study, 27.3% were spastic diplegic, 37.4% were spastic quadriparesic and 32.4% were spastic hemiplegic. This is little different from European countries spastic diplegia percentage found as 40.9% -54.9% and spastic quadriparesic CP as 18% -20.8% (11).But it is similar to Eltallawy et al, (2014) (8) who reported that 35% were spastic diplegic, 22% were spastic quadriparesic and 15.5% were spastic hemiplegic.…”

“…Regarding to study carried out in AL-Kharga DistrictNew-valley (EGYPT), Shevell and Bodensteiner (2004) (7) recorded that the most commonly recorded risk factors were grandparents' consanguinity (50%), Parents' consanguinity was recorded in 34.6% of participants. Eltallawy et al, (2014) (8) reported in his result that positive consanguinity presented in (48%)…”

“…Laisram and et al, (1992) (11) and jhonston and Hagberg (2007) (12) reported that the risk of CP is significantly greater in males than in females. Eltallawy et al, (2014) (8) reported the ratio was 1.22-1 boy to girl.…”

“…Clark and Hankins (2013) (14) and Lilford and et al, (1990) (15) recorded that although it seems intuitively reasonable that a speedy delivery might occasionally rescue an infant from potential harm, there is no evidence of good quality that surgical delivery can prevent CP. Eltallawy et al, (2014) (8) reported that cesarean section presented in (64%)and normal delivery presented in(36%)…”

“…Blair and Waston (2006) (4) reported that Spasticity was typically cited as the predominant motor type, occurring in 77% to 93% of CP cases, dyskinesia in 2% to 15%, and ataxia in 2% to 8%. Eltallawy etal., (2014) (8) reported that spastic CP was 72.5%, Dyskinetic was 16%, Ataxic was 7%, Hypotonic was 4.5%…”