Cerebral Organoid Arrays for Batch Phenotypic Analysis in Sections and Three Dimensions
Juan Chen,
Haihua Ma,
Zhiyu Deng
et al.
Abstract:Organoids can recapitulate human-specific phenotypes and functions in vivo and have great potential for research in development, disease modeling, and drug screening. Due to the inherent variability among organoids, experiments often require a large sample size. Embedding, staining, and imaging each organoid individually require a lot of reagents and time. Hence, there is an urgent need for fast and efficient methods for analyzing the phenotypic changes in organoids in batches. Here, we provide a comprehensive… Show more
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