Cerebral Malaria and Neuronal Implications of Plasmodium Falciparum Infection: From Mechanisms to Advanced Models (Adv. Sci. 36/2022)

Abstract

Plasmodium falciparum Infection Cerebral malaria is the most severe complication caused by the malaria parasite P. falciparum . In article number 2202944 , Oscar Bate Akide Ndunge, Nicole Kilian, and Mootaz M. Salman review the pathogenic mechanisms that underlie the development of this fatal condition. Moreover, they discuss the current understanding and recent developments in diagnostic and treatment methods as well as advanced models to study and eventually tackle this devastating disease using organ‐on‐a‐chip and humanised systems.