Abstract:PLATES I1 AND 111) EARLY in 1957 work was started in the Department of Surgery of the University of Birmingham on a method of total cardiopulmonary bypass for eventual use on patients needing open cardiac surgery. It was decided to use the Lillehei-DeWall system, already employed successfullyin theunited States, in which oxygen is bubbled through a vertical column of blood (" bubble oxygenation ") (Lillehei et al., 1957). The reasons for selecting this particular apparatus for use in Birmingham have been given… Show more
“…Ashton, quoted by Smith (1959) noted circular capillary "holes" in the renal glomeruli of dogs subjected to total cardiopulmonary by-pass using a bubble-oxygenator. He assumed that these were embolic silicone lesions.…”
Section: Effects Of Extracorporeal Circulation On the Kidneys And Thementioning
confidence: 99%
“…Taylor (1958) described similar neurological damage and Yates et al (1959) demonstrated silicone emboli histologically. Smith (1959) examined the brains of 39 dogs subjected to extracorporeal circulation in Birmingham using a bubble-oxygenator. He found histological evidence of extensive silicone embolism in 28 animals (72 per cent) including lesions in 18 dogs which survived for 14 days after total cardiopulmonary by-pass without obvious clinical neurological damage.…”
Section: Effects Of Extracorporeal Circulation On the Brainmentioning
“…Ashton, quoted by Smith (1959) noted circular capillary "holes" in the renal glomeruli of dogs subjected to total cardiopulmonary by-pass using a bubble-oxygenator. He assumed that these were embolic silicone lesions.…”
Section: Effects Of Extracorporeal Circulation On the Kidneys And Thementioning
confidence: 99%
“…Taylor (1958) described similar neurological damage and Yates et al (1959) demonstrated silicone emboli histologically. Smith (1959) examined the brains of 39 dogs subjected to extracorporeal circulation in Birmingham using a bubble-oxygenator. He found histological evidence of extensive silicone embolism in 28 animals (72 per cent) including lesions in 18 dogs which survived for 14 days after total cardiopulmonary by-pass without obvious clinical neurological damage.…”
Section: Effects Of Extracorporeal Circulation On the Brainmentioning
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