Cerebral insult-like partial status epilepticus in the early-onset variant of benign childhood epilepsy with occipital paroxysms

Panayiotopoulos, C. P.; Igoe, Derval

doi:10.1016/1059-1311(92)90006-m

Cited by 15 publications

(12 citation statements)

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“…A very recent multicenter study involving 139 patients used the same methods (18). In addition, the number of patients was small or the follow-up period was not long enough, or both, in several studies (1 I,] 4,16,17). This raises the possibility of selecting patients with good outcomes retrospectively and thereby the exclusion of those with a poor prognosis.…”

Section: Discussionmentioning

confidence: 99%

Study on the Early‐Onset Variant of Benign Childhood Epilepsy with Occipital Paroxysms Otherwise Described as Early‐Onset Benign Occipital Seizure Susceptibility Syndrome

et al. 1999

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Summary: Purpose: We studied the early-onset variant of benign childhood epilepsy with occipital paroxysms (EVBCEOP) proposed by Panayiotopoulos, to confirm whether his five criteria are sufficient to delineate EVBCEOP as a new epileptic syndrome, as well as to predict a good outcome prospectively at the time of the first examination.Subjects: The subjects were 649 children with localizationrelated epilepsies (LREs) observed in our hospital for >4 years.Methods: We applied the International Classification of Epilepsies and Epileptic Syndromes to the 649 patients and identified patients who had EVBCEOP from among those with nonspecific idiopathic LRE. The inclusion criteria were to satisfy all five criteria and all but one criterion (i.e., either ictal vomiting or occipital EEG paroxysms). We were blind as to the outcomes and selected patients who satisfied the following teria, 22 who exhibited all but occipital EEG foci, and 2 1 who exhibited all but ictal vomiting. The incidence of status convulsivus was higher in those with ictal vomiting than in those without ictal vomiting (p < 0.05). Interictal EEG performed every 6 months showed shifting and multiplication of EEG foci in 42 and 52% of all subjects, respectively. We identified 57 patients, 42 (74%) of whom were in remission by age 12 years. The number of patients who experienced remission did not differ significantly between those with (76%, n = 25) and without (72%, n = 32) ictal vomiting (p > 0.05). Conclusions:Nosologically, EVBCEOP appears to constitute the earliest form of idiopathic epileptic syndrome different from classic BCEOP. However, its clinical spectrum, ranging from the absence of ictal vomiting to a combination of extraoccipital and multifocal EEG foci, is broad, such that further three of the five criteria at the time of the first examination, (a) normal development before the onset, (b) epilepsy onset age between 2 and 8 years, and (c) occipital EEG foci. We attempted to determine whether the outcome can be predicted prospectively, and whether the presence or absence of ictal vomiting affects the prognosis.Results: We identified 19 patients who satisfied all five criprospective study is expected to reveal the exact prerequisite criteria for determining the border of this epileptic syndrome and for clarifying the clinical spectrum within this syndrome. Key Words: Early-onset variant of benign childhood epilepsy with occipital paroxysms-Migrating EEG foci-Ictal vomiting-Idiopathic localization-related epilepsy-Occipital EEG foci.Panayiotopoulos proposed classifying benign childhood epilepsy with occipital paroxysms (BCEOP) into early-onset and late-onset types based on the results of his 15-year prospective follow-up study of children with occipital paroxysms (1-8). In his proposal, the latter is classified as BCEOP (9), which Gastaut originally defined, and visual seizures are the predominant seizure type. The early-onset type has been proposed to be a new idiopathic epileptic syndrome, characterized by the fol-~ ~~~

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Section: Discussionmentioning

confidence: 99%

Study on the Early‐Onset Variant of Benign Childhood Epilepsy with Occipital Paroxysms Otherwise Described as Early‐Onset Benign Occipital Seizure Susceptibility Syndrome

et al. 1999

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“…Другим специфичным клиническим признаком, опи-санным при идиопатической затылочной эпилепсии детского возраста, был инсультоподобный эпилепти-ческий статус парциальных приступов с вегетативны-ми симптомами [18,35,40]. Чтобы подчеркнуть ва-риабельность проявлений доброкачественных фокальных эпилептических синдромов в детстве, С. Panayiotopoulos и его коллеги использовали термин «доброкачественный синдром детского возраста, пред-располагающий к приступам» [29,30].…”

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Early Onset Benign Childhood Occipital Epilepsy (Panayiotopoulos Syndrome). A Case Report

Матюк¹,

Котов²,

Борисова³

et al. 2015

Rus. ž. det. nevrol.

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“…3). The association of prolonged seizures and tonic eye deviation and ictal vomiting (i.e., Panayiotopoulos-type CEOP) has been previously described (5,8,13,(35)(36)(37)(38), although one study (38) emphasized that the occipital spikes were not reactive to eye opening.…”

Section: Figmentioning

confidence: 99%

Childhood Epilepsy With Occipital Paroxysms: Clinical Variants in 134 Patients

2000

Epilepsia

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Summary:Purpose: In its recent proposal, the Commission on Classification and Terminology of the International League Against Epilepsy classified childhood epilepsy with occipital paroxysms (CEOP) into two syndromes with different predominant seizure types: early onset (Panayiotopoulos type) with eye deviation and ictal vomiting and late onset (Gastaut type) with initial ictal visual symptoms. We documented the clinical features of a large group of patients with CEOP to confirm whether the classification is justified.Methods: A file review of all patients with partial-onset seizure and interictal occipital spikes referred to our pediatric seizure unit between January 1975 and May 1997 yielded 134 who met the criteria for CEOP. Data were collected with a specially developed protocol and classified according to the two International League Against Epilepsy systems: (a) seizure classification, to test age-specific differences associated with the predominant seizure type, and (b) syndrome classification, to determine whether the clusters of signs and symptoms are sufficiently delineated.Results: Three groups were defined according to the predominant ictal manifestations. Group 1 (visual) consisted of 24 patients (17.9%) with ictal visual symptoms; 19 (14%) of these patients also had overlapping adversive manifestations, either as a separate seizure or as part of the same event (median age at first and last seizure, 7 years 11 months and 10 years). Group 2 (adversive) consisted of 72 patients (53.7%) with tonic eye deviation (median age at first and last seizure, 5 years 2 months and 7 years 2 months). Group 3 (nonvisual, nonadversive) consisted of 38 patients (28.4%) with various seizure spread patterns (median age at first and last seizure, 6 and 7 years 2 months). Two syndromes were identified. The Gastaut type included all 24 patients in the visual group (group 1); seizures were brief and frequent and were diurnal in 83%. The Panayiotopoulos type included all 72 patients in group 2; ictal eye deviation occurred in 100% of the patients and ictal vomiting in 44%; prolonged seizures were observed in 35% and were more frequent in patients who had ictal vomiting than in those who did not (46.8% versus 25%, respectively; p < 0.027). Seizures were infrequent; 24% of patients had a single seizure and 58% had nocturnal seizures. Onset was earlier than for the Gastaut type (p < 0.002). The 38 patients with nonoccipital manifestations did not satisfy the criteria for the complete form of either syndrome.Conclusions: The most common type of CEOP, the Panayiotopoulos type, is characterized by a cluster of signs and symptoms sufficiently delineated to justify their separate classification from Gastaut-type CEOP, despite the absence of ictal vomiting in more than 50% of the patients.

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Cerebral insult-like partial status epilepticus in the early-onset variant of benign childhood epilepsy with occipital paroxysms

Cited by 15 publications

References 9 publications

Study on the Early‐Onset Variant of Benign Childhood Epilepsy with Occipital Paroxysms Otherwise Described as Early‐Onset Benign Occipital Seizure Susceptibility Syndrome

Study on the Early‐Onset Variant of Benign Childhood Epilepsy with Occipital Paroxysms Otherwise Described as Early‐Onset Benign Occipital Seizure Susceptibility Syndrome

Early Onset Benign Childhood Occipital Epilepsy (Panayiotopoulos Syndrome). A Case Report

Childhood Epilepsy With Occipital Paroxysms: Clinical Variants in 134 Patients

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