Cerebral hyperperfusion syndrome following LVAD implantation

Boyle, A.J; Park, S.J; Colvin-Adams, Monica; Liao, Kenneth; Ormaza, Sofia; Thompson, Joshua A.; Miller, Leslie W.

doi:10.1016/s1053-2498(02)01092-6

Cited by 5 publications

(2 citation statements)

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“…Cerebral hyperfusion syndrome, an early neurological complication most commonly associated with carotid endarterectomy, has also been reported in mechanical circulatory support recipients (13). This syndrome, a result of prolonged hypoperfusion and impaired autoregulation of cerebral blood flow, results in increases of cerebral blood flow of up to 100% over baseline following intervention, and can also lead to cerebral edema and stroke.…”

Section: Addressing Neurological Complicationsmentioning

confidence: 97%

“…In the single report of this syndrome occurring in mechanical circulatory support patients, Boyle et al. implemented device flow restrictions in two patients which led to complete neurological recovery (13). These findings suggest that there may be some potential strategies of implementing innovative device operating modes which allow for a more gradual restoration of blood flow levels post implant.…”

Section: Addressing Neurological Complicationsmentioning

confidence: 99%

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Neurological Dysfunction Associated With Mechanical Circulatory Support: Complications That Still Need Attention

Mussivand

2008

Artificial Organs

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Section: Addressing Neurological Complicationsmentioning

confidence: 97%

Section: Addressing Neurological Complicationsmentioning

confidence: 99%

Neurological Dysfunction Associated With Mechanical Circulatory Support: Complications That Still Need Attention

Mussivand

2008

Artificial Organs

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Does cognition improve following LVAD implantation?

Pavol

Willey

Wei

et al. 2018

Gen Thorac Cardiovasc Surg

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We found significantly improved cognition 3 months after LVAD surgery in a subset of patients without post-surgical stroke. The reasons for the lack of cognitive improvement at the 1-month post-surgical assessment may include ongoing medical and physiological disruptions in the immediate post-operative period. Further research into the sources of delayed improvement is warranted. Cognitive assessments performed immediately after surgery should be interpreted with caution because the results may not reflect longer term cognitive outcomes. LVAD patients may require additional support to successfully manage their health in the weeks immediately following surgery but assistance needs may decrease over time.

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