Cerebral fat emboli syndrome: do not miss the transcranial Doppler findings

Saleh, Mohamed; Juan, Emmanuelle

doi:10.1136/bcr-2015-210445

Cited by 2 publications

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References 2 publications

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“…Another TCD parameter to take into account for CFE diagnosis is the occurrence of a very high mean velocity value (about 160 cm/sec) associated with a markedly dilated arterial diameter. These findings are highly suggestive of marked hyperemia associated with the biochemical pathogenesis of CFE 69…”

Section: Introductionmentioning

confidence: 85%

From the diagnosis to the therapeutic management: cerebral fat embolism, a clinical challenge

Scarpino¹,

Lanzo²,

Lolli³

et al. 2019

IJGM

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Cerebral fat embolism (CFE) is an uncommon incomplete type of fat embolism syndrome (FES), characterized by purely cerebral involvement. It usually occurs 12–72 hours after the initial trigger, mainly represented by closed, long-bone multiple fractures of the lower extremities. Neurological manifestations are mainly characterized by headache, confusion, seizures, focal deficit, and alteration of the consciousness state up to coma onset. It represents a diagnostic challenge, above all when secondary to uncommon nontraumatic causes, because neurological signs and symptoms are variable and nonspecific, not satisfying the Gurd and Wilson’s criteria, the diagnostic features most widely used today for FES diagnosis. Neuroimaging (mainly MRI, but in some cases, brain computed tomography too) can hasten the diagnosis, avoiding other unnecessary investigations and treatment. Usually self-limiting, CFE may sometimes be fatal. Treatment is to date mainly supportive and prophylactic strategies are considered an important tool to decrease the development of fat embolism and, consequently, the rate of CFE.

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Section: Introductionmentioning

confidence: 85%