Cerebral Cysticercosis.

Ohnishi, Koji; Murata, Misako; Nakane, Makoto; Takemura, Nobuhiko; Tsuchida, T.; Nakamura, Takahide

doi:10.2169/internalmedicine.32.569

Cited by 7 publications

(4 citation statements)

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“…They all were suspected of exposure to the eggs of T. solium in countries of endemicity outside Japan (in Asia and Latin America). Five samples were from patients with single cysts in the brain; four of these were Japanese, and one was Nepali (12,16;Ito et al,unpublished data). Three samples were from patients with multiple cysts in the brain, one from Brazil and two from Peru.…”

Section: Methodsmentioning

confidence: 99%

Molecular Characterization and Diagnostic Value of Taenia solium Low-Molecular-Weight Antigen Genes

et al. 2000

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Neurocysticercosis (NCC) caused by infection with the larvae ofTaenia solium is an important cause of neurological disease worldwide. In order to establish an enzyme-linked immunosorbent assay (ELISA) for this infection using recombinant proteins, we carried out molecular cloning and identified four candidates as diagnostic antigens (designated Ag1, Ag1V1, Ag2, and Ag2V1). Except for Ag2V1, these clones could encode a 7-kDa polypeptide, and Ag2V1 could encode a 10-kDa polypeptide. All of the clones were very similar. Except for Ag2V1, recombinant proteins were successfully expressed using anEscherichia coli expression system. Immunoblot analysis of NCC patient sera detected recombinant proteins, but because reactivity to recombinant Ag1 was too weak, Ag1 was not suitable as an immunodiagnostic antigen. So, Ag1V1 and Ag2 were chosen as ELISA antigens, and the Ag1V1/Ag2 chimeric protein was expressed. Of 49 serum samples from NCC patients confirmed to be seropositive by immunoblot analysis, 44 (89.7%) were positive by ELISA. No assays of serum samples from patients with other parasitic infections recognized the Ag1V1/Ag2 chimeric protein. The Ag1V1/Ag2 chimeric protein obtained in this study had a high value for differential immunodiagnosis.

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Section: Methodsmentioning

confidence: 99%

Molecular Characterization and Diagnostic Value of Taenia solium Low-Molecular-Weight Antigen Genes

et al. 2000

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“…NCCis the most common,serious and life-threatening disease due to T. solium infection (3). In 33 reported cysticercosis cases from 1983 until 1992 in Japan, 31 cases were NCC, and 24 had had experience of visiting or staying in endemic regions of T. solium infection (8). Endemic regions include almost all Latin America, Southeast Asia, South Africa and other African countries (4,9).…”

Section: Discussionmentioning

confidence: 99%

Neurocysticercosis without Detectable Specific Antibody.

et al. 1999

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A 19-year-old girl who had lived in India for five years until 1992 was admitted to Hokuto Hospital after general seizures which lasted for fifteen minutes. Cerebral magnetic resonance imaging (MRI) showed a ring-enhanced lesion of 6 mmin diameter in the right parietal lobe. She underwent surgical resection after diagnosis of the brain tumor. Histopathological examinations revealed that the resected tumor was a cysticercus of Taenia solium (T. solium), and weconcluded that her seizures were caused by neurocysticercosis. Serological examinations by enzyme-linked immunosorbent assay (ELISA) and immunoblots to detect specific antibody against the glycoproteins of T. solium showedno detectable antibody response. The patient is under careful observation in our outpatient clinic with no medication.

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“…However, 13 cases have suggested that infection occurred within Japan (cases 1 [55], 8 [50,51], 10 [56], 12 [57], 20 [54], 21 [58], 22 [59], 23 [60], 28 [9], 40 [22], 52 [36], 53, and 62 [40]. NCC was diagnosed by imaging findings (Fig.…”

Section: Clinical Casesmentioning

confidence: 99%

Current Status and Perspectives of Cysticercosis and Taeniasis in Japan

Yamasaki

2013

Korean J Parasitol

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This mini-review describes recent epidemiological trends in cysticercosis and taeniasis in Japan. Some of the topics discussed herein were presented at the first symposium on "Current perspectives of Taenia asiatica researches", that was held in Osong in Chungbuk Province, South Korea, in October 2011 and organized by Prof. K. S. Eom, Chungbuk National University School of Medicine. To better understand the trends in the occurrence of cysticercosis and taeniasis in Japan, clinical cases reported in 2005 have been updated. In addition, the current status of Taenia asiatica infections successively occurring in Japan since 2010 is also discussed.

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Cerebral Cysticercosis.

Cited by 7 publications

References 0 publications

Molecular Characterization and Diagnostic Value of Taenia solium Low-Molecular-Weight Antigen Genes

Molecular Characterization and Diagnostic Value of Taenia solium Low-Molecular-Weight Antigen Genes

Neurocysticercosis without Detectable Specific Antibody.

Current Status and Perspectives of Cysticercosis and Taeniasis in Japan

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