Cerebral cortical blood flow during changes of acid-base equilibrium of the brain.

Betz, E.; Heuser, D.

doi:10.1152/jappl.1967.23.5.726

Cited by 108 publications

(44 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This correlation is at variance with the results of Betz et al (1966Betz et al ( , 1967Betz et al ( , 1968 which demonstrated a reproducible relationship of CBF as measured by heat clearance and by 85Kr washout in the same animal, with variations between animals. It must be kept in mind that their probe differed from the one used in this experiment in two important respects: (1) the size of the cortical contact surface, and (2) the temperature of the non-heated plate.…”

Section: Discussionsupporting

confidence: 74%

See 1 more Smart Citation

Cortical blood flow in controlled hypotension as measured by thermal diffusion

Carter

Atkinson

1973

Journal of Neurology, Neurosurgery & Psychiatry

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 74%

“…Betz and Wiillenweber (1962), Betz, Ingvar, Lassen, and Schmahl (1966), Betz and Heuser (1967), Betz (1968), using a technique described by Hensel (1959), have made extensive measurements of cerebral cortical blood flow. Their probe had two small gold plates, one heated and one neutral, which were placed on the cortex.…”

mentioning

confidence: 99%

Cortical blood flow in controlled hypotension as measured by thermal diffusion

Carter

Atkinson

1973

Journal of Neurology, Neurosurgery & Psychiatry

View full text Add to dashboard Cite

show abstract

“…10 This effect develops rather slowly, peaking after 10 minutes, and is a very strong vasodilatory stimulus. 11 Acetazolamide increases cerebral blood flow (CBF) usually to a greater extent than that induced by 5 minutes of 5% CO 2 inhalation. vasodilatory capacity in 16 of 18 cases when measuring CBF by xenon-133-inhalation tomography and the acetazolamide test in patients with ICA occlusions before and after EC-IC bypass surgery.…”

Section: S Ince Publication Of the Results Of The Internationalmentioning

confidence: 99%

Evaluation of vasomotor reactivity by transcranial Doppler and acetazolamide test before and after extracranial-intracranial bypass in patients with internal carotid artery occlusion.

Karnik

Valentin

Ammerer

et al. 1992

Stroke

View full text Add to dashboard Cite

Background and Purpose:The aim of this trial was to evaluate the effectiveness of extracranialintracranial bypass with respect to vasomotor reactivity in patients with internal carotid artery occlusions and absent vasomotor reactivity, comparing them with a control group treated conservatively.Methods: To test vasomotor reactivity in 104 patients with unilateral occlusion of the internal carotid artery, we measured blood flow velocity in the middle cerebral artery by transcranial Doppler sonography both at rest and after injection of acetazolamide. Among the 39 patients who failed to show increased mean blood flow velocity after the acetazolamide test distal to an occluded internal carotid artery by 2:10%, 14 subjects subsequently underwent extracranial-intracranial bypass surgery (group A) and 14 age-and sex-matched subjects in whom no such procedure was done composed the control group (group B). Follow-up examinations were performed 3-6 months postoperatively and in the control group 3-6 months after initial examination.Results: Baseline values of the mean blood flow velocity at rest on the affected side were reduced in both groups compared with the contralateral healthy side (group A, 46.0±15.1 cm/sec; group B, 48.1 ±16.7 cm/sec) and revealed only a marginal increase after acetazolamide. The contralateral side showed a normal blood flow velocity at rest and an adequate response to acetazolamide in both groups. On the follow-up examination group A demonstrated a normalized vasodilatory capacity. Blood flow velocity increased significantly after acetazolamide from 41.9±13.1 cm/sec to 53.5±16.0 cm/sec (p<0.002). In group B, the compromised vasomotor reactivity remained unchanged.Conclusions: Our results demonstrate that transcranial Doppler sonography together with the acetazolamide test can identify subjects with reduced vasomotor reactivity distal to an occluded internal carotid artery, who may improve hemodynamically by an extracranial-intracranial bypass. (Stroke 1992^3:812-817) KEY WORDS • acetazolamide • cerebral revascularization • ultrasonics

show abstract

“…Accepted for publication June 12, 1972. cerebral blood flow have been measured during respiratory acidosis and alkalosis (7)(8)(9) and during enhanced activity of the cerebral cortex (10)(11)(12), it would be of interest to investigate whether changes in blood flow are at least partially mediated by alterations in the extravascular K + concentration. Therefore, the influence of the perivascular K + concentration on the resistance of pial arteries was studied.…”

mentioning

confidence: 99%