Cerebral Amyloid Angiopathy, Hemorrhages and Superficial Siderosis

Superficial siderosis in the general population

“…A possible explanation may then be sought in intrinsic (genetic) differences in heme and iron metabolism that influence the clearance of hemorrhage from the brain. 13 Our population-based study design enabled us to study superficial siderosis outside a clinical setting in persons without dementia. 4 The superficial siderosis in these patients was primarily located in the temporal region, while in our asymptomatic participants there appeared to be a frontal and occipital predilection of siderosis.…”

Identification of mineral deposits in the brain on radiological images: a systematic review

“…2 and Electronic Supplementary Material). We also considered five reviews (one on calcium [10], three on iron [6,[11][12][13]) and one editorial [14] that discussed the MRI signal changes associated with mineral deposition along with pathological findings as well as the biochemistry and pathophysiology surrounding them, but they were excluded from the statistical analysis.…”