Cerebral abscesses in behçet’s disease: a case report

Tokgöz, Serhat; Öğmegül, Ayşegül; Mutluer, Muzaffer; Kivrak, Ali Sami; Üstün, Mehmet Erkan

doi:10.5137/1019-5149.jtn.3297-10.2

Cited by 3 publications

(2 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cerebral abscesses are rare, serious, and life-threatening complications in BD. Although there are various hypotheses regarding the cause of abscesses, including bacterial, viral or fungal infections, no microbial agent has been confirmed [ 30 ]. According to nationwide surveys performed in Iran, Japan, China, Korea and Germany, neurological manifestations were diagnosed respectively in 9%, 11%, 6.5%, 4.6%, and 11% of patients with BD [ 19 ].…”

Section: Neurological Involvementmentioning

confidence: 99%

Morbus Behçet – a rare disease in Central Europe

Woźniacka¹,

Sysa-Jędrzejowska²,

Jurowski³

et al. 2015

aoms

View full text Add to dashboard Cite

Behçet's disease (BD) is a multiorgan inflammatory disease of complex and not entirely elucidated etiology, which was originally diagnosed in patients with aphthous stomatitis, genital ulcerations and ocular manifestations. The entity is endemic in countries of Eastern and Central Asia, especially Turkey and Iran, but rarely seen in Central Europe. As there are no specific diagnostic laboratory tests or histopathologic findings which confirm the preliminary diagnosis, the final diagnosis should be based on clinical criteria. Frequently a definitive diagnosis is established within several years or months after the first manifestations appear. The increased number of cases, recently described worldwide also in the Polish population, indicates that the disease could spread out of endemic areas. The aim of this manuscript is to present the clinical picture, diagnosis criteria and therapeutic approaches of this “international disease” which currently is observed not only in emigrants from Asia but also in native Polish citizens.

show abstract

Section: Neurological Involvementmentioning

confidence: 99%

Morbus Behçet – a rare disease in Central Europe

Woźniacka¹,

Sysa-Jędrzejowska²,

Jurowski³

et al. 2015

aoms

View full text Add to dashboard Cite

show abstract

“…The relationship between vasculitis and S. epidermidis infection in the development of aneurysm is still unknown. 52 Iliopoulos et al described tuberculous meningoencephalitis in a patient with BD. 47 Nevertheless, the presence of infection was not proven.…”

Section: Common Infections In Bd Patientsmentioning

confidence: 99%

Infection and Behçet Disease

Correia

Campar

Ferrão

et al. 2015

Infection and Autoimmunity

View full text Add to dashboard Cite

Behçet’s disease complicated by multiple aseptic abscesses of the liver and spleen

Maeshima

Ishii

Inoue³

et al. 2013

WJG

View full text Add to dashboard Cite

Aseptic abscesses are an emergent entity and have been described in inflammatory bowel disease, especially in Crohn's disease, and in other diseases. However, aseptic abscesses associated with Behçet's disease are extremely rare. We report a Japanese male diagnosed with an incomplete type of Behçet's disease who developed multiple aseptic abscesses of the spleen and liver. In 2002, the spleen abscesses were accompanied by paroxysmal oral aphthous ulcers and erythema nodosum. As the patient's response to antibiotic treatment was inadequate, a splenectomy was performed. Severe inflammatory cell infiltration, largely of polymorphonuclear neutrophils, was observed without evidence of bacterial or fungal growth. Although the patient had no history of ocular symptoms or genital ulcers, a diagnosis of incomplete Behçet's disease was made according to the Japanese diagnostic criteria because of the presence of paroxysmal arthritis and epididymitis since 2002. In 2005, multiple liver abscesses developed with right hypochondrial pain and seemed to be attributed to Behçet's disease because the abscesses yielded negative results during a microbiologic investigation and failed to go into remission under antibiotic therapy. Oral prednisone (15 mg/d) was started in May 2006, and the abscesses dramatically disappeared 4 wk after treatment. Although the patient had a relapse of the liver abscesses in association with the tapering of prednisone, the augmentation of prednisone dosage yielded a response. The abscesses of the liver and spleen were strongly suggested to be attributed to Behçet's disease. Clinician should be aware of the existence of aseptic abscesses as uncommon manifestations of Behçet's disease.

show abstract

Cerebral abscesses in behçet’s disease: a case report

Cited by 3 publications

References 3 publications

Morbus Behçet – a rare disease in Central Europe

Morbus Behçet – a rare disease in Central Europe

Infection and Behçet Disease

Behçet’s disease complicated by multiple aseptic abscesses of the liver and spleen

Contact Info

Product

Resources

About