“…But its activity against clinically relevant pathogens is not satisfactory in cases of severe life threatening or aesthetically compromising infections of the head and neck (Reinhardt et al, 1986;Al-Nawas et al, 2000;Mylonas et al, 2007;Snydman et al, 2007). According to some authors, more than 90% of the infections are polymicrobial with anaerobes playing an important role (Calhoun et al, 1988;Spaey et al, 2005;Skitarelic et al, 2007), the analogy to mixed abdominal and skin infections becomes obvious.…”