Cerebellar metastases: diagnostic and management considerations.

Fadul, Camilo E.; Misulis, Karl E.; Wiley, Ronald G.

doi:10.1200/jco.1987.5.7.1107

Cited by 46 publications

(26 citation statements)

References 14 publications

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“…71 The most common primary tumor site is the lung, with the breast, melanoma, and colon making up a large proportion of the rest. 70 Headache is more common than dizziness, but the 2 symptoms often co-occur. Because headache is uncommon in vestibular neuritis, co-occurrence of headache and dizziness in AVS usually suggests a central cause such as stroke or mass lesion.…”

Section: Posterior Fossa Neoplasms and Other Mass Lesionsmentioning

confidence: 99%

“…In one series of patients, a cerebellar metastasis caused the presenting symptoms in 25% of cases (15 of 59). 70 Therefore, even in a patient without a known history of a systemic cancer, a new cerebellar mass could be due to a metastasis. Analysis of registry data suggests that cerebellar location of brain metastases is increasing.…”

Section: Posterior Fossa Neoplasms and Other Mass Lesionsmentioning

confidence: 99%

See 1 more Smart Citation

Medical and Nonstroke Neurologic Causes of Acute, Continuous Vestibular Symptoms

Edlow

Newman‐Toker

2015

Neurologic Clinics

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Section: Posterior Fossa Neoplasms and Other Mass Lesionsmentioning

confidence: 99%

Section: Posterior Fossa Neoplasms and Other Mass Lesionsmentioning

confidence: 99%

Medical and Nonstroke Neurologic Causes of Acute, Continuous Vestibular Symptoms

Edlow

Newman‐Toker

2015

Neurologic Clinics

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“…Despite these precautions, the risk of a decompensating obstructive hydrocephalus or of intratumoural haemorrhage with increased intracranial pressure may remain, and preliminary shunting should be considered, Notwithstanding a higher chance of postoperative complications when compared with supratentorial lesions [32], surgical extirpation of a cerebellar metastasis seems to carry a smaller risk of an acutely decompensating increased intracranial pressure than radiotherapy alone [11].…”

Section: Cerebellar Metastasesmentioning

confidence: 99%

Clinical management of brain metastasis

Vecht

1998

J Neurol

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Brain metastasis is a common complication occurring in about 15-20% of all cancer patients. For the initial management, distinguishing between three types of presentation is essential: de novo brain metastasis, simultaneous presentation of both brain metastasis and the primary tumour (usually lung carcinoma), and the presentation of a patient known to have systemic cancer developing a brain metastasis. For de novo brain metastasis, surgery is required, and detecting the primary tumour is of limited value. For simultaneous presentation, both a craniotomy and a thoracotomy may be indicated and may lead to cure in a number of cases. For a sequential presentation, the outcome is determined by a number of independent prognostic factors: age, performance status, and the extent of metastatic disease. In relatively young patients with a single brain metastasis, good performance status and no progression of systemic disease, treatment by either surgery or radiosurgery in combination with whole brain radiation therapy is indicated. Otherwise, as in multiple brain metastases, radiation therapy only is the main treatment. For symptomatic therapy of brain oedema or increased intracranial pressure, dexamethasone is administered. The standard doses of dexamethasone may vary between 4 and 16 mg/day, depending on the severity of symptoms.

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“…Başağrısı, başdönmesi, nöbet, bulantı, kusma gibi şikayetlerle başvururlar (3). Metastazın lokalizasyonuna göre hemiparezi, ataksi, afazi gibi bulgular oluşabilir (4 …”

Section: Introductionunclassified

Supra- and Infratentorial Cystic Metastases of Breast Cancer: Case Report

Tatarlı¹,

Gergin²,

Özdoğan³

et al. 2016

Acta Oncol Tur.

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ÖZETMeme kanserinin kranial metastazları; kemik, dura veya beyin parankimine olmaktadır. Semptomlar metastazın lokalizasyonuna göre değişir. Kitleler; solid, kistik veya parsiyel kistik şekilde olabilirler. Meme kanserinin kistik intrakranial metastazları oldukça nadirdir. Cerrahi sonrası radyoterapi ve/veya kemoterapi uygulanır. Kırksekiz yaşında bayan olgu, baş ağrısı ve generalize tonik-klonik nöbet şikayetleri ile başvurdu. Sekiz yıl önce sol meme kanseri nedeniyle sol total mastektomi ve sol koltukaltı lenfadenektomi ameliyatı yapılmış. Patolojisi adenoid kistik karsinom olarak gelmiş. Lenf nodlarında metastaz tespit edilen olguya adjuvan kemoterapi uygulanmış. Meme ameliyatından sekiz yıl sonra yapılan kranial MRG'sinde (Manyetik Rezonans Görüntüleme) sol frontalde ve serebellar orta hatta büyük kistik kitle lezyonları tespit edildi. Yapılan PET-CT (Pozitron Emisyon Tomografi) incelemesinde, başka herhangi bir organında metastaz tespit edilmedi. Meme açısından yapılan genel cerrahi konsültasyonunda herhangi bir patoloji bulunmadı. Her iki kranial lezyon nedeniyle bir hafta arayla iki kez ameliyat edilen olgunun yapılan patolojik incelemesinde, kistik meme kanseri metastazı tespit edildi. Ameliyat sonrasında olguya tüm beyin radyoterapi uygulandı. Kemoterapi uygulanmadı. Bu olgu dolayısıyla kranial kistik metastazlarda, ender de rastlansa meme kanseri metastazlarını ayırıcı tanıda düşünmemiz gerektiğini vurgulamak istedik. Anahtar Kelimeler: Kistik intrakranial metastaz, meme kanseri, kistik metastaz, beyin metastazı ABSTRACT Breast cancer is most frequently metastasize dura, bone and parenchyma in cranial tissue. Symptoms vary according to the location of the metastasis. Masses may be solid, cystic and partial cystic form. Cystic intracranial metastases of breast cancer is very rare. Radiotherapy and/or chemotherapy could be performed after surgery. Forty-eight-year-old female patient was admitted with complaints of headache and generalized tonicclonic seizure. Patient underwent surgery for cancer of the left breast for eight years ago. Left total mastectomy and left axillary lymphadenectomy was performed. Pathology was determined as adenoid cystic carcinoma. Adjuvant chemotherapy was applied to patients with lymph nodes metastasis detected. Cranial MRI (Magnetic Resonance Imagination) was performed after eight years after breast surgery. In the left frontal and cerebellar midline, large cystic mass lesions were detected in cranial MRI. PET-CT (Positron Emission Tomography) examination was not detected in any other organ metastases. There was no pathology in terms of breast surgery consultation. Both cranial lesions were underwent surgery twice in one week. In the pathological examination of the patient, cystic breast cancer metastasis was detected. Whole brain radiotherapy was performed to the patient after surgery. We want to emphasize that in cranial cystic metastasis, rarely come across if breast cancer metastasis should be considered in differential diagnosis.

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Cerebellar metastases: diagnostic and management considerations.

Cited by 46 publications

References 14 publications

Medical and Nonstroke Neurologic Causes of Acute, Continuous Vestibular Symptoms

Medical and Nonstroke Neurologic Causes of Acute, Continuous Vestibular Symptoms

Clinical management of brain metastasis

Supra- and Infratentorial Cystic Metastases of Breast Cancer: Case Report

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