Cercaricidal activity of some essential oils of plants from Brazil

Frischkorn, C. G. B.; Frischkorn, H. E.; Carrazzoni, E.P.

doi:10.1007/bf00702834

Cited by 33 publications

(15 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…22 Cercaricide property was atributted to the oil and leaves of caapeba-cheirosa. 82 The sesquiterpenes β-caryophyllene and germacrene D predominate in the oils of caapeba [Pothomorphe peltata (L.) Miq. and P. umbellata (L.) Miq., Piperaceae].…”

Section: Results and Discussion The Inventory Of The Aromatic Floramentioning

confidence: 99%

Database of the Amazon aromatic plants and their essential oils

Maia¹,

Andrade²

2009

Quím. Nova

107

View full text Add to dashboard Cite

The aromatic flora of the Amazon has been inventoried for 30 years. In this sense, were made over 500 field trips to collect over 2500 plants and to obtain more than 2000 essential oils and aroma concentrates, all of them submitted to GC and GC-MS. This work led to the creation of a database for the aromatic plants of the Amazon, which catalogs general information about 1250 specimens. The database has allowed the publication of the chemical composition of the oils and aromas of more than 350 species, associated with a larger number of chemical types. The essential oils of many species offer optimum conditions for economic exploitation and use in national and international market of fragrances, cosmetics, agricultural and household pesticides

show abstract

Section: Results and Discussion The Inventory Of The Aromatic Floramentioning

confidence: 99%

Database of the Amazon aromatic plants and their essential oils

Maia¹,

Andrade²

2009

Quím. Nova

107

View full text Add to dashboard Cite

show abstract

“…An earlier study on Dugesia (Baguna et al., 1989) showed that 10 −6 M capsaicin stimulated cell division, while 100-fold higher concentrations (10 −4 M) appeared to kill the worms. Finally, oil extracts of the leaves and fruit of the Brazilian pepper Capsicum annuum , which likely contain capsaicin, were shown to kill 90–96% of S. mansoni cercariae within 15 min (Frischkorn et al., 1978). However, an oil extract of the marigold pepper Piper marginatum , which is not a chili pepper (genus Capsicum ), and presumably does not contain capsaicin (Barceloux, 2009), had a similar effect on cercariae, suggesting that the killing of cercariae by these extracts may be independent of capsaicin.…”

Section: Capsaicin and Other Trpv1 Channel Modulators Affect Schistosmentioning

confidence: 99%

TRP channels in schistosomes

Bais

Greenberg

2016

International Journal for Parasitology: Drugs and Drug Resistan

View full text Add to dashboard Cite

Praziquantel (PZQ) is effectively the only drug currently available for treatment and control of schistosomiasis, a disease affecting hundreds of millions of people worldwide. Many anthelmintics, likely including PZQ, target ion channels, membrane protein complexes essential for normal functioning of the neuromusculature and other tissues. Despite this fact, only a few classes of parasitic helminth ion channels have been assessed for their pharmacological properties or for their roles in parasite physiology. One such overlooked group of ion channels is the transient receptor potential (TRP) channel superfamily. TRP channels share a common core structure, but are widely diverse in their activation mechanisms and ion selectivity. They are critical to transducing sensory signals, responding to a wide range of external stimuli. They are also involved in other functions, such as regulating intracellular calcium and organellar ion homeostasis and trafficking. Here, we review current literature on parasitic helminth TRP channels, focusing on those in schistosomes. We discuss the likely roles of these channels in sensory and locomotor activity, including the possible significance of a class of TRP channels (TRPV) that is absent in schistosomes. We also focus on evidence indicating that at least one schistosome TRP channel (SmTRPA) has atypical, TRPV1-like pharmacological sensitivities that could potentially be exploited for future therapeutic targeting.

show abstract

“…The essential oils from the oleoresins of several Protium spp. have been shown to possess antimicrobial, antiinflammatory, antinociceptive, antioxidant, antitumor, acaricidal, molluscicidal and cercaricidal activities [2,[16][17][18][19][20][21]. Some of these activities have also been reported for the volatile oils from other parts of the plants, mainly leaves and fruits [1,2].…”

mentioning

confidence: 99%

Composition and Biological Activity of Essential Oils from Protium confusum

Santana

Vila

Espinosa

et al. 2009

Natural Product Communications

View full text Add to dashboard Cite

The composition and biological activity of the essential oils from leaves, fruits, stems and bark of Protium confusum are reported for the first time. Forty-six to sixty-three constituents were identified ranging from 73.8% to 98.5% of the samples. Limonene (60.2%) was the main component in the fruit oil, whereas spathulenol (19.3%), β-caryophyllene oxide (14.1%) and β-caryophyllene (8.0%) reached the highest percentages in the oil from leaves. The volatile oils from bark and stems showed the same major constituents: p-cymen-8-ol (14.4% and 6.1%, respectively), spathulenol (9.5% and 9.0% respectively), and hexadecanoic acid (8.4% and 7.8%, respectively). The composition of the essential oils differed significantly from those of previously investigated Protium species. Three out of the four samples exhibited antibacterial activity against Staphylococcus aureus and Mycobacterium smegmatis, the one from leaves being the most active, with MIC values of 62.5 μg/mL in both cases. No activity against Candida albicans was detected. The bark oil showed the highest larvicidal activity against Aedes aegypti (LC 100 = 125 μg/mL).

show abstract

Cercaricidal activity of some essential oils of plants from Brazil

Cited by 33 publications

References 3 publications

Database of the Amazon aromatic plants and their essential oils

Database of the Amazon aromatic plants and their essential oils

TRP channels in schistosomes

Composition and Biological Activity of Essential Oils from Protium confusum

Contact Info

Product

Resources

About