Cephalosporins: Use Review and Cost Analysis

Noel, Michael W.; Paxinos, James

doi:10.1093/ajhp/35.8.933

American Journal of Health-System Pharmacy

1978

DOI: 10.1093/ajhp/35.8.933

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Cephalosporins: Use Review and Cost Analysis

Michael W. Noel

James Paxinos

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Cited by 10 publications

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“…But, this required a decrease in the prescribed dose, since cefazolin is less expensive on a perday basis only if appropriately used. 2 Phelps and Godwin described how the Kansas University Medical Center Pharmacy and Therapeutics Committee made a formulary cephalosporin choice based on both pharmacologie and cost data. Their approach, similar to ours, utilized pharmacy department recommendations for formulary drug selection in an effort to maintain an effective formulary that would realize maximal cost savings.…”

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Effectiveness of a Cephalosporin Education Program —A Pharmacy Education Program

Sohn¹,

Wolter²,

McSweeney³

1980

Drug Intelligence & Clinical Pharmacy

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In October, 1977, a cephalosporin drug-use review and an educational program were initiated to maximize savings in the pharmacy budget at UCSF and to revise the formulatory to include only one parenteral cephalosporin. The results of the drug-use review were presented to the Pharmacy and Therapeutics Committee where our proposal for an education campaign to encourage appropriate dosing of cefazolin was approved. An explanatory document comparing cephalosporin costs and equivalency was developed for hospital-wide distribution. Pharmacy staffs were informed of program objectives to coordinate education efforts. Physician education was undertaken via document and personal contact with pharmacy personnel. A drug-use review one month after institution of the cephalosporin education program showed marked changes in physician prescribing habits, with greater impact on services where pharmacists were members of the medical rounding team. A change to appropriate dosage prescribing of cefazolin resulted in significant cost savings to the pharmacy budget. These findings resulted in formulary revision to cefazolin as the single cephalosporin available at UCSF. Because cefazolin is available from more than one manufacturer, we were able to obtain a lower bid price the following year, thus realizing an additional cost savings.

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mentioning

confidence: 99%

Effectiveness of a Cephalosporin Education Program —A Pharmacy Education Program

Sohn¹,

Wolter²,

McSweeney³

1980

Drug Intelligence & Clinical Pharmacy

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Practical strategies for the appropriate use of antimicrobials

1995

Pharm World Sci

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The use and misuse of antimicrobial agents is well documented in the literature. A variety of mechanisms has been used to enhance the appropriate use of these agents. A widely used initial strategy is the formation of multidisciplinary groups, such as Pharmacy and Therapeutics Committees or antimicrobial subcommittees, which are responsible for all antimicrobial policies for the health-care facility. Other techniques include the use of antimicrobial order sheets, automatic stop orders, therapeutic substitution, antibiotic restriction systems, and the use of selective antimicrobial susceptibility reporting systems. Many of these strategies have been reported to be effective in the management of antimicrobial usage; however, they also result in increased administrative and monitoring costs. Antimicrobial control systems must be individualized to the health-care facility.

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Use of Antimicrobial Drugs in General Hospitals. II. Analysis of Patterns of Use

Shapiro

Townsend

Rosner

et al. 1979

Journal of Infectious Diseases

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The hospital charts were surveyed of 5,288 patients in 20 hospitals that were randomly selected from the 194 general hospitals in Pennsylvania. Antimicrobial drugs were administered to 28% of the patients, with little variation in pattern according to hospital size. Surgical services accounted for 61% of the patients who received antimicrobial drugs, and the proportion of patients receiving such drugs varied from 84% on thoracic and cardiovascular surgical services to 13% on obstetrical services. General medicine accounted for 29% of the patients who received antimicrobial drugs and pediatrics for 9%. Eight percent of the hospital population accounted for 50% of all antimicrobial drugs used. Ampicillin was the most frequently used drug, being given in 22% of all courses, with cephalosporins (18%), benzylpenicillins (14%), and tetracycline (13%) next in order. Approximately 30% of the antimicrobial courses were used for prophylaxis.

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Cephalosporins: Use Review and Cost Analysis

Cited by 10 publications

References 0 publications

Effectiveness of a Cephalosporin Education Program —A Pharmacy Education Program

Effectiveness of a Cephalosporin Education Program —A Pharmacy Education Program

Practical strategies for the appropriate use of antimicrobials

Use of Antimicrobial Drugs in General Hospitals. II. Analysis of Patterns of Use

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