The relationship between fetal biparietal diameter (BPD) and menstrual age was determined by cross-sectional analysis of 533 fetuses (12 to 40 weeks) examined with a linear array real-time (dynamic image) scanner using specifically defined methodology. Mathematical modeling of the data demonstrated that the optimal fit was the linear cubic function (r = 99 per cent); predicted BPD values calculated from the function were most comparable with composite data from cross-sectional studies performed with static scanners after 1974 (average difference, 0.22 mm) and least comparable with composite data from cross-sectional studies performed with static scanners before 1974 (average difference, 2.0 mm). The variability associated with predicting menstrual age from the BPD increased progressively throughout gestation; the maximal variability was noted between 36 and 42 weeks (±3.6 weeks). Comparison with our longitudinal study of BPD growth indicates that the cross-sectional data represent a valid estimate of the true longitudinal BPD growth curve of the population. (Key words: fetal biparietal diameter; fetal age, determination of; ultrasonographic cephalometry; real-time ultrasound.) Several investigators have made comparative measurements of the fetal biparietal diameter (BPD) using real-time and static-image ultrasound scanners, and the results have indicated that the measurement differences are not statistically significant. The conclusion of these studies is that real-time determinations of the BPD may be applied to BPD/gestational age charts generated by static image equipment. 1 -5 A problem remains, however, in deciding which static-image BPD chart to use, since there are discrepancies among charts from different institutions. For example, the original data from Yale 8 differs at some points by as much as three weeks' gestation from the values reported by Sabbagha and Hughey. 7 Some investigators have attempted to solve this problem by making composite charts 7 -9 using data from as many as 17 institutions. But there are problems with such charts: 1) these composite charts do not agree specifically on mean values or, more importantly, on the range of standard devia- tion values at various points in gestation; 2) although large numbers of measurements were used to construct each chart, there is no indication of whether there was an equal distribution of measurements made at various points in gestation; 3) the number of measurements exceeds the number of patients, indicating that some patients were measured more than once during gestation, which is known to increase the possibility of bias in crosssectional data 10 ; 4} the specific anatomy of the plane of section used for measuring the biparietal diameter of the fetal skull was not indicated in these studies; and 5) the gain settings and transducer frequency were either not indicated or not uniform in the individual studies.The use of real~time ultrasound has greatly facilitated identification of specific planes of section in the fetal brain 11 and thus pro...