CeO₂ nanoparticles: A robust and reusable heterogeneous catalyst for the diastereoselective synthesis of β-acetamido esters

Abstract

The preparation of seven β-acetamido esters, two of which are novel, has been achieved by a one-pot condensation reaction of an araldehyde, ethyl acetoacetate and acetyl chloride in the presence of CeO2 nanoparticles under reflux conditions in acetonitrile. This method provides several advantages including easy workup, excellent yields, short reaction times, diastereoselective synthesis, reusability of the catalyst and low catalyst loading.

Synthesis of Bis‐Thiazolidinones Using Chitosan‐attached Nano‐CuFe2O4 as an Efficient and Retrievable Heterogeneous Catalyst

“…Despite the availability of these methods, there remains adequate interest to find new routes for efficient, high‐yielding, and mild approaches to achieve such systems. The eco‐compatibility and employability of MCRs increase when theMCRs are used in association with a heterogeneous catalyst . Chitosan is a biopolymer that can be used as a green catalyst in many reactions .…”