Centriolar satellites are sites of translation of centrosomal and ciliary proteins
Claudia Pachinger,
Jeroen Dobbelaere,
Cornelia Rumpf-Kienzl
et al.
Abstract:Centriolar satellites are cytoplasmic particles found in the vicinity of centrosomes and cilia whose functional contribution to the formation of these cellular structures has long been unclear. By characterizing the main scaffolding component of satellites, PCM1 or Combover inDrosophila, we show that satellites are not involved in cellular trafficking as previously thought but rather act as sites for the coordinate translation of centrosomal and ciliary proteins through the interaction with a set of RNA bindin… Show more
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