Centrifugo-Pneumatic Reciprocating Flowing Coupled with a Spatial Confinement Strategy for an Ultrafast Multiplexed Immunoassay
Chungen Qian,
Pengjie Li,
Jingjing Wang
et al.
Abstract:Immunoassays serve as powerful diagnostic tools for early disease screening, process monitoring, and precision treatment. However, the current methods are limited by high costs, prolonged processing times (>2 h), and operational complexities that hinder their widespread application in point-of-care testing. Here, we propose a novel centrifugo-pneumatic reciprocating flowing coupled with spatial confinement strategy, termed PRCM, for ultrafast multiplexed immunoassay of pathogens on a centrifugal microfluidic p… Show more
“…13–16 This innovation arranges microfluidic channels and reaction chambers on a rotating disk, harnessing the mechanical effects of centrifugal force, Coriolis force, and Euler force generated during disk rotation. 17–21 This enables precise manipulation and operation of samples and reagents. 22–30…”
“…13–16 This innovation arranges microfluidic channels and reaction chambers on a rotating disk, harnessing the mechanical effects of centrifugal force, Coriolis force, and Euler force generated during disk rotation. 17–21 This enables precise manipulation and operation of samples and reagents. 22–30…”
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