Central venous-to-arterial CO2 difference/arterial-central venous O2 difference ratio: An experimental model or a bedside clinical tool?

He, Huaiwu; Liu, Dawei

doi:10.1016/j.jcrc.2016.05.009

Cited by 10 publications

(2 citation statements)

References 11 publications

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“…Moreover, the further correction of P V-A CO 2 by C A-V O 2 can further increase the degree of anaerobic metabolism. It is interesting that many scholars have different judgment of the critical value of P V-A CO 2 by C A-V O 2 ratio in different clinical studies, [7,[25][26][27] which may be due to more variables in the formula resulting in increased measurement error and uncertainty of the results.…”

Section: Discussionmentioning

confidence: 99%

Association between initial microcirculation disturbance patients and mortality in patients who are critically ill: A retrospective cohort study

Guo,

Zheng,

et al. 2023

Medicine

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Impact of microcirculation status from mortality of critically ill population has been investigated for decades, but the prognosis of early initial microcirculation disturbance in critically ill population in the intensive care unit remains to be explored. The cohort study was conducted using the medical information database for intensive care IV. Critically ill adult in intensive care unit have been enrolled and categorized by early microcirculation status. Cox Proportional-Hazards models have been utilized for testing intermediaries and assess the relationship between combined early initial microcirculation disturbance and mortality. Several 2286 patients were initially screened. Some patients with a highest lactate level >2.2 mmol/L on the firstly day of admission (n = 1468) were then extracted for further analysis. 735 patients received in the initial microcirculation disturbance group as well as 733 patients were in the hyperlactatemia group. In those with elevated lactate, the 28-day mortality of early microcirculation disturbance was higher than that of hyperlactatemia alone (7-day mortality [16.19% vs 12.68%; Adjusted hazard ratio 1.35, 95% confidence intervals 1.03 to 1.78, P = .029], 28-day mortality [33.33% vs 27.28%; adjusted HR 1.34, 95% confidence interval 1.11 to 1.67, P = .002]). Early microcirculatory disturbances (increased PV-ACO2/CA-VO2 ratio and higher initial blood lactate level) were more reliable predictors of in-hospital mortality than early isolated lactate elevation.

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Section: Discussionmentioning

confidence: 99%

Association between initial microcirculation disturbance patients and mortality in patients who are critically ill: A retrospective cohort study

Guo,

Zheng,

et al. 2023

Medicine

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“…Elevated lactate does not always reflect tissue hypoxia or anaerobic metabolism it ranges between 1.4-1.68 mmHg/mL (38)(39)(40). Figure 7 shows the algorithm for hemodynamic monitoring using blood gas analysis.…”

Section: Venous-to-arterial Carbon Dioxide Pressure Difference (∆P(v-a)co2)mentioning

confidence: 99%

Hemodynamic monitoring with two blood gases: “a tool that does not go out of style”

Sánchez-Díaz

Moguel

Rivera-Solís

et al. 2020

Colomb. J. Anesthesiol.

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Introduction. Hemodynamic monitoring of a critically ill patient is an indispensable tool both inside and outside intensive care; we currently have invasive, minimally invasive and non-invasive devices; however, no device has been shown to have a positive impact on the patient's evolution; arterial and venous blood gases provide information on the patient's actual microcirculatory and metabolic status and may be a hemodynamic monitoring tool. Objective. To carry out a non-systematic review of the literature of hemodynamic monitoring carried out through the variables obtained in arterial and venous blood gases. Material and methods. A non-systematic review of the literature was performed in the PubMed, OvidSP and ScienceDirect databases with selection of articles from 2000 to 2019. Results. It was found that there are variables obtained in arterial and venous blood gases such as central venous oxygen saturation (SvcO2), venous-to-arterial carbon dioxide pressure (∆pv-aCO2), venous-to-arterial carbon dioxide pressure/arteriovenous oxygen content difference (∆pv-aCO2/∆Ca-vO2) that are related to cellular oxygenation, cardiac output (CO), microcirculatory veno-arterial flow and anaerobic metabolism and allow to assess tissue perfusion status. Conclusion. The variables obtained by arterial and venous blood gases allow for non-invasive, accessible and affordable hemodynamic monitoring that can guide medical decision-making in critically ill patients.

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Understanding elevated Pv-aCO2 gap and Pv-aCO2/Ca-vO2 ratio in venous hyperoxia condition

Liu

İnce

2017

J Clin Monit Comput

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Central venous-to-arterial CO2 difference/arterial-central venous O2 difference ratio: An experimental model or a bedside clinical tool?

Cited by 10 publications

References 11 publications

Association between initial microcirculation disturbance patients and mortality in patients who are critically ill: A retrospective cohort study

Association between initial microcirculation disturbance patients and mortality in patients who are critically ill: A retrospective cohort study

Hemodynamic monitoring with two blood gases: “a tool that does not go out of style”

Understanding elevated Pv-aCO2 gap and Pv-aCO2/Ca-vO2 ratio in venous hyperoxia condition

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