Central venous saturation is not an alternative to mixed venous saturation during cardiopulmonary bypass in coronary artery surgery patients

Abstract

Although mean biases between the measurements were low, limits of agreement were too large to provide a clinically acceptable estimation of SvO(2) by ScvO(2) in these conditions. Variations in regional oxygen consumption seem to be the main factor worsening the relationship.

Perioperative estimations of oxygen consumption from LiDCO™plus-derived cardiac output and Ca-cvO2 difference: Relationship with measurements by indirect calorimetry in elderly patients undergoing major abdominal surgery

“…The 20-minute data extraction periods in this study were specifically chosen to represent perioperative time points that usually are without considerable circulatory instability. Central and mixed venous oxygen saturation have not shown interchangeability [ 46 – 48 ] but some studies have suggested that trends in ScvO 2 can replace SvO 2 [ 49 – 51 ]. During stable intraoperative conditions, oxygen content difference is not expected to vary to a large extent whereas cardiac output can show considerable in- and between patient variability [ 21 ].…”

Perioperative changes in oxygen consumption: estimations from minimal-invasive cardiac output and a-cvO2 difference parallel to indirect calorimetry

“…(30, 47) The 20-minute data extraction periods in this study were specifically chosen to represent perioperative time points that usually are without considerable circulatory instability. Central and mixed venous oxygen saturation have not shown interchangeability(48-50) but some studies have suggested that trends in ScvO 2 can replace SvO 2 . (51-53) During stable intraoperative conditions, oxygen content difference is not expected to vary to a large extent whereas cardiac output can show considerable in- and between patient variability.…”

Agreement between Central and Mixed Venous Oxygen Saturation Following Cardiac Surgery

“…Alshaer et al [8] examined the correlation during beating heart coronary surgery and concluded that SvO 2 and ScvO 2 are not interchangeable numerically but ScvO 2 can be useful if used as a trend. Soussi et al [9] concluded that central venous saturation can not be an alternative to mixed venous saturation during cardiopulmonary bypass.…”

“…The previous studies evaluating the relationship between ScvO 2 and SvO 2 showed a significant variation in results because of different study designs and clinical setup which included intensive care patients with either sepsis, heart failure, or shock [4][5][6][7]. Studies involving such relationship during and after cardiac surgery [8][9][10][11][12][13][14][15] also showed contradicting results, this controversy is generating confusion among clinicians and further work is needed to explore this area.…”