Central venous catheter-related complications in newborns and infants: A 587-case survey

Goutail-Flaud, M.F.; Sfez, Michel; Berg, Alain; Laguenie, G.; Couturier, Christian; Barbotin-Larrieu, F.; Saint-Maurice, C

doi:10.1016/0022-3468(91)90001-a

Cited by 110 publications

(49 citation statements)

References 15 publications

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“…19 Catheters placed in the superior or inferior vena cava may be complicated by thrombosis or hydrothrorax, but these complications are usually more benign than pericardial tamponade. 1,11,12 We suggest the following strategy will prevent deaths from tamponade:…”

Section: Darling Et Almentioning

confidence: 99%

Central Venous Catheter Tip in the Right Atrium: A Risk Factor for Neonatal Cardiac Tamponade

et al. 2001

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Section: Darling Et Almentioning

confidence: 99%

Central Venous Catheter Tip in the Right Atrium: A Risk Factor for Neonatal Cardiac Tamponade

et al. 2001

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“…In studies focused on the pediatric population, the frequency of deep vein thrombosis related to centrally inserted venous catheters has varied from 11% to 50%. 1,5,6,8,11 In the past 10 years, peripherally inserted central catheters (PICC) have been used with increasing frequency in children and adolescents. The catheter is inserted percutaneously via a peripheral vein, with its tip residing in the superior vena cava.…”

mentioning

confidence: 99%

Incidence of deep vein thrombosis related to peripherally inserted central catheters in children and adolescents

Dubois

Rypens²,

Garel³

et al. 2007

Canadian Medical Association Journal

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“…7 Although PCVC is the preferred route of venous access in many NICUs, it has some complications such as mechanical problems and infections. 8,9 The common mechanical complication is catheter occlusion, and it can occur in 15 to 48% of placed PCVCs. 10 Few earlier studies supporting the use of heparin suggest that it decreases the risk of blockage in the PCVC.…”

Section: Introductionmentioning

confidence: 99%

The effect of low-dose heparin on maintaining peripherally inserted percutaneous central venous catheters in neonates

et al. 2010

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Objective: To evaluate the effect of low-dose heparin on duration of peripherally inserted percutaneous central venous catheter (PCVC) patency and catheter occlusion.Study Design: Our research was a prospective, randomized, controlled, double-blind clinical study including 246 eligible neonates with PCVCs. It was conducted at the neonatal intensive care unit (NICU) of Diyarbakir Children's Hospital between 1 February 2007 and 31 October 2008. In the heparin group (n ¼ 118), the total parenteral nutrition (TPN) solutions contained heparin, which was infused at a rate of 0.5 IU kg À1 h À1. The no-heparin group (n ¼ 121) received TPN fluids without heparin.Result: In the heparin group, the duration of catheter patency was longer than that of the no-heparin group reaching a statistically significant difference (12.4 ± 4.5 vs 9.7 ± 4.0, P<0.0001). In the heparin group, the proportion of patients completing the TPN therapy successfully was higher than in the no-heparin group (P ¼ 0.0001; relative risk (RR): 3.32 (95% confidence interval (CI): 1.92 to 5.73)) also demonstrating a statistically significant difference. The rate of catheter occlusion among infants in the heparin group was smaller (P ¼ 0.0001; RR: 3.44 (95% CI: 1.92 to 6.44)). There were no statistically significant differences between the two groups in the incidence of other catheter-related problems. The length of the occluded catheter outside the skin, TPN infusion rate and catheter duration time were found to be the factors associated with catheter occlusion. Heparin prevented catheter occlusion with a mechanism unrelated to these factors. Conclusion:In neonates with PCVCs, low-dose continuous infusion of heparin (0.5 IU kg À1 h À1 ) within TPN fluids is an effective measure in terms of reducing catheter occlusion, allowing successful completion of the therapy, without increasing adverse effects. Furthermore, this effect of heparin may occur independently via occlusion-related factors that we evaluated in the study.

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Central venous catheter-related complications in newborns and infants: A 587-case survey

Cited by 110 publications

References 15 publications

Central Venous Catheter Tip in the Right Atrium: A Risk Factor for Neonatal Cardiac Tamponade

Central Venous Catheter Tip in the Right Atrium: A Risk Factor for Neonatal Cardiac Tamponade

Incidence of deep vein thrombosis related to peripherally inserted central catheters in children and adolescents

The effect of low-dose heparin on maintaining peripherally inserted percutaneous central venous catheters in neonates

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