Central Venous Access Port-related Complications in Outpatient Chemotherapy for Colorectal Cancer

Abstract

Technical troubles involving ports and pumps occurred at a certain rate, and skin incision was required for system exchange in some cases. When performing outpatient chemotherapy using ports and pumps, thorough prior guidance and double-checking must be implemented, and proper countermeasures must be established.

Economic and patient-reported outcomes of outpatient home-based versus inpatient hospital-based chemotherapy for patients with colorectal cancer

“…In general, patients receiving FOLFOX treatment are required to be hospitalized because chemotherapy requires continuous infusion of medication over about 46 h. Additionally, the 2-week chemotherapy schedule causes frequent hospitalization. However, in recent years, homebased chemotherapy has become possible by placing a central venous access port (CV port) and using a portable, disposable pump [1,5]. Effective antitumor activity and a safe toxicity profile for the FOLFOX regimen administered on a home basis have been demonstrated for patients with colorectal cancer [13,14].…”

“…Additionally, patients can reduce their health care spending by avoiding hotel costs associated with a hospital stay [12,17]. On the other hand, patients may encounter complications involving CV ports and pumps [5]. Patients may have difficulty in dealing with these complications and managing the injection site by themselves outside a hospital setting.…”

“…Concerns regarding such potential difficulties may make patients reluctant to take the option of homebased chemotherapy. However, a number of clinical studies have demonstrated that home-based chemotherapy is effective and safe, with a minor complication profile involving CV ports and pumps [3,5,15].…”

The duration of functioning of a subcutaneous implantable port for the treatment of hematological tumors: a single institution-based study

“…Subcutaneous implantable ports have been commonly used for patients with solid tumors [2,3]; for the treatment of metastatic colorectal cancer (mCRC), an implantable port in combination with a disposable portable pump has facilitated complicated chemotherapy regimens, including the continuous infusion of 5-fluorouracil, in the outpatient setting [4,5]. As a result, patients with mCRC routinely live longer than 2 years [6].…”

Mechanical Thrombolysis of Thrombosed Central Venous Port

“…Complications after CVP implantation have been well described [1][2][3][4][5]. Postprocedural CVP system-related complications can be divided into three categories: infectious, venous thrombotic, and mechanical [1].…”