Central serous retinopathy and hand&amp;ndash;foot&amp;ndash;mouth disease: coincidence or causation?

Taylor, Selina; Khan, Maureen; Zaidi, Shams; Alvi, Umair; Fatima, Yaqoot

doi:10.2147/imcrj.s181088

Cited by 3 publications

(2 citation statements)

References 22 publications

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“…Early intervention should therefore be considered. Currently, no standard therapy for acute CSC is available, even though many treatment modalities, such as thermal laser photocoagulation, photodynamic therapy with verteporfin, micropulse diode laser photocoagulation, and pharmacological agents, have been used as treatment [10][11][12][13][14][15]. These interventions are not appropriate for all cases, a problem that warrants research on novel solutions.…”

Section: Introductionmentioning

confidence: 99%

Using oral Rifampin to treat acute central serous Chorioretinopathy: a randomized placebo-controlled clinical trial ‎

Alizadeh¹,

Akbari²,

Soltanipour³

et al. 2022

J Adv Pharm Educ Res

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Section: Introductionmentioning

confidence: 99%

Using oral Rifampin to treat acute central serous Chorioretinopathy: a randomized placebo-controlled clinical trial ‎

Alizadeh¹,

Akbari²,

Soltanipour³

et al. 2022

J Adv Pharm Educ Res

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“…FMDV is pathogenic to more than 100 domestic and wild animal species [3][4][5]. FMDV also affects humans [6].…”

Section: Introductionmentioning

confidence: 99%

Genetic Polymorphisms of Foot-and-Mouth Disease Virus

Ildarovich¹

2021

Some RNA Viruses

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The aim of the work is to search for loci of the genome of various types of foot-and-mouth disease virus (FMDV), characterized by the lowest variability, for use as genetic markers in the polymerase chain reaction (PCR) of virus identification. The nucleotide sequences of the genomes of FMDV of types A, Asia-1, C, O, and SAT (1, 2, and 3) were analyzed. When aligning the genomes of isolates of each type of virus, potentially conservative sites were identified. Comparing these loci, different types of the virus have one, the most conserved locus. Subsequent basic local alignment search tool (BLAST) analysis established the correspondence of the conservative locus to the FMDV genome, and primers and a probe were developed to amplify this locus.

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Hand, Foot, and Mouth Disease: A Narrative Review

Leung

Lam

Barankin³

et al. 2022

RAIAD

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Background: Hand, foot, and mouth disease is a common viral disease in childhood. Because the disease has the potential to reach epidemic levels and the mortality is high in some countries, early recognition of this disease is of paramount importance. Objective: This purpose of this article is to familiarize pediatricians with the clinical manifestations and management of hand, foot, and mouth disease. Methods: A search was conducted in February 2022 in PubMed Clinical Queries using the key term " hand, foot, and mouth disease". The search strategy included all clinical trials, observational studies, and reviews published within the past 10 years. Only papers published in the English literature were included in this review. Results: Hand, foot, and mouth disease is characterized by a painful oral enanthem and asymptomatic exanthem on the palms and soles. Children younger than 5 years are most commonly affected. Hand, foot, and mouth disease caused by enterovirus A71 is more severe and has a higher rate of complications than that attributed to other viruses such as coxsackievirus A16. Circulatory failure secondary to myocardial impairment and neurogenic pulmonary edema secondary to brainstem damage are the main causes of death. Fortunately, the disease is usually benign and resolves in 7 to10 days without sequelae. Given the self-limited nature of most cases, treatment is mainly symptomatic and supportive. Intravenous immunoglobulin should be considered for the treatment of severe/complicated hand, foot, and mouth disease and has been recommended by several national and international guideline committees. Currently, there are no specific antiviral agents approved for the treatment of the disease. Drugs such as ribavirin, suramin, mulberroside C, aminothiazole analogs, and sertraline have emerged as potential candidates for treatment of hand, foot, and mouth disease. Vaccination of susceptible individuals in high-risk areas and good personal hygiene are important preventative measures to combat the disease. Conclusion: Familiarity of the disease including its atypical manifestations is crucial so that a correct diagnosis can be made, and appropriate treatment initiated. A timely diagnosis can help avoid contact with the affected individual and decrease the risk of an outbreak.

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Central serous retinopathy and hand–foot–mouth disease: coincidence or causation?

Cited by 3 publications

References 22 publications

Using oral Rifampin to treat acute central serous Chorioretinopathy: a randomized placebo-controlled clinical trial ‎

Using oral Rifampin to treat acute central serous Chorioretinopathy: a randomized placebo-controlled clinical trial ‎

Genetic Polymorphisms of Foot-and-Mouth Disease Virus

Hand, Foot, and Mouth Disease: A Narrative Review

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