Central serous chorioretinopathy following intravenous steroid therapy for retrobulbar optic neuritis – “Treatment dilemma” – Case report and review of literature

Mohan, Roshni; Mohankumar, Arthi; Basker, Ayshwaria; Sivakumar, Priya

doi:10.4103/tjosr.tjosr_163_20

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…Central serous chorioretinopathy has also been reported in association with topical minoxidil use [ 21 , 22 ]. This is proposed to occur through increased choroidal and retinal vascular vessel permeability secondary to increased sympathetic activity, increased VEGF, and potential direct effects on ion and fluid balance [ 21 , 22 ]. Similarly, increased vascular permeability may have contributed to CME in the present case.…”

Section: Discussionmentioning

confidence: 99%

From Hair Loss to Vision Loss: Minoxidil-Associated CRVO in a Young Female

Pickel,

Ji,

Abdelazim

et al. 2024

Case Rep Ophthalmol

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Introduction: Central retinal vein occlusion (CRVO) is a common retinal vascular disorder that is most often seen in older adults and individuals with vascular risk factors. Case Presentation: We report a case of CRVO with cystoid macular edema (CME) in a young, otherwise healthy patient taking minoxidil for hair loss. The patient had no known vascular risk factors, and a comprehensive coagulability workup was negative. The CRVO with CME resolved without intervention upon cessation of minoxidil. Conclusion: Possible mechanisms for minoxidil-associated retinal vascular disorders are explored. Thorough medication histories and the consideration of possible adverse drug events in patients without traditional risk factors are recommended.

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Section: Discussionmentioning

confidence: 99%

From Hair Loss to Vision Loss: Minoxidil-Associated CRVO in a Young Female

Pickel,

Ji,

Abdelazim

et al. 2024

Case Rep Ophthalmol

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“…Mohan et al [ 22 ] pointed out that in cases of pathologies that need to be treated by corticosteroids, the patients must be informed and warned about the adverse effects of the treatment.…”

Section: Discussionmentioning

confidence: 99%

A 30-Year-Old Man with a Recent History of COVID-19 Requiring Treatment with Corticosteroids Who Developed Bilateral Central Serous Chorioretinopathy During 7-Month Follow-Up

Angelidis,

Georgalas,

Giachos

et al. 2023

Am J Case Rep

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Patient: Male, 30-year-old Final Diagnosis: Retinopathy Symptoms: Visual acuity worsening Clinical Procedure: — Specialty: Ophthalmology Objective: Unusual clinical course Background: Central serous chorioretinopathy (CSCR) involves a localized serous macular detachment, secondary to retinal pigment epithelial and choroidal vascular changes, which can be an adverse effect of corticosteroid use. Most CSCR cases resolve spontaneously, and normal vision returns, while some chronic cases can result in blindness. This report is of a 30-year-old man with a recent history of Corona virus disease (COVID)-19 requiring corticosteroid treatment who developed bilateral CSCR with unilateral fibrin and a 7-month follow-up. Case Report: A 30-year-old male patient presented with malaise and high fever. The patient tested positive for COVID-19, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus and was admitted. During hospitalization, he received intravenous (IV) corticosteroids for 1 week (6 mg dexamethasone IV once daily). Following hospitalization, the patient received per os methylprednisolone 16 mg (16 mg once daily for 3 days, 8 mg once daily for 3 days, 4 mg once daily for 3 days, and 2 mg once daily for 3 days). One month later, the patient presented with bilateral visual acuity (VA) deterioration and acute CSCR. The diagnosis and follow-up were performed by optical coherence tomography (OCT) and fundus fluorescein angiography (FFA). The patient was followed-up for a period of 7 months, during which, although the VA improved and remained stable, the OCT findings were changing. Conclusions: This report highlights the importance of timely ophthalmological examination in patients with sudden vision loss and identification of the association between corticosteroid use and CSCR, as well as the importance of a longer follow-up period.

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Central serous chorioretinopathy following intravenous steroid therapy for retrobulbar optic neuritis – “Treatment dilemma” – Case report and review of literature

Cited by 2 publications

References 8 publications

From Hair Loss to Vision Loss: Minoxidil-Associated CRVO in a Young Female

From Hair Loss to Vision Loss: Minoxidil-Associated CRVO in a Young Female

A 30-Year-Old Man with a Recent History of COVID-19 Requiring Treatment with Corticosteroids Who Developed Bilateral Central Serous Chorioretinopathy During 7-Month Follow-Up

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