Central serous chorioretinopathy complicating inflammation suppressive treatment

Abstract

SummaryCentral serous chorioretinopathy (CSC) can sometimes be mistaken for posterior uveitis. Its diagnosis is of utmost importance as CSC as failure to do so will worsen when steroid therapy is erroneously given. The situation is even more tricky when CSC is complicating IST including steroids given for uveitis. In a collective of 1739 patients seen from 1995 to 2014 at the COS, 16 patients (0.9%) with CSC were misdiagnosed as posterior uveitis of which the development of CSC was missed in 4 uveitis patients under IST including corticosteroids. The mean diagnostic delay in the latter group was 2.4 ± 1.9 months, substantially shorter than the group of patients misdiagnosed at the onset (56.3 ± 60.6 months). The key to rapid diagnosis of a decrease of VA due to CSC in uveitis, is to search on one side whether inflammatory parameters such as laser flare photometry and dual fluorescein (FA) and indocyanine green angiography (ICGA) are improving combined with the search of CSC signs including serous detachments and/or small PEDs on OCT as well as typical CSC angiographic signs on dual FA/ICGA angiography. Although CSC complicating uveitis treatment is rare, prompt diagnosis is of utmost importance to avoid deleterious consequences.

Drug-Induced Myopia: Pathogenesis, Diagnosis, and Treatment

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