Central Sensitization in Chronic Low Back Pain: A Population-Based Study of a Japanese Mountain Village

Akeda, Koji; Takegami, Norihiko; Yamada, Jun−ichi; Fujiwara, Takanori; Nishimura, Akinobu; Sudo, Akihiro

doi:10.2147/jpr.s301924

Cited by 12 publications

(8 citation statements)

References 44 publications

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“…We must discuss the pain intensity evaluated with the NRS score, the disability in daily life evaluated with the RDQ score, and the impact of LBP on work of the subjects. The NRS and RDQ scores of our subjects with LBP at baseline were lower than those of the patients with LBP [ 24 , 32 ] and even the community dwellers with LBP [ 33 ]. Regarding the impact on work, approximately three-quarters of the subjects with LBP at baseline felt slight pain occasionally.…”

Section: Discussionmentioning

confidence: 84%

Psychosocial work characteristics and low back pain in daycare (nursery) workers in Japan: a prospective cohort study

Shi

Aoshima

Iida

et al. 2022

BMC Musculoskelet Disord

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Background Low back pain (LBP) is one of the most common musculoskeletal problems affecting daycare (nursery) workers. We aimed to identify the psychosocial factors influencing LBP in daycare workers. Methods We conducted a prospective cohort study with a one-year observation period. The baseline sample was a convenience sample of 444 daycare workers from 34 daycare facilities in Nagoya, Japan, and its suburbs. All the data were collected through a questionnaire survey. The question “Where are you currently feeling LBP?” was used to determine whether the subjects suffered from LBP. We examined the prospective relationships of the psychosocial work characteristics, i.e., high job strain, low social support, effort-reward imbalance, and overcommitment, at baseline and LBP after one year. We used multiple logistic regression analyses to calculate the odds ratios of psychosocial work characteristics for the persistence and onset of LBP, adjusted for age, sex, body mass index, smoking, employment status, occupation, and working schedule. Results At baseline, 270 (60.8%) subjects suffered from LBP. Of 208 who also gave information on LBP one year later, 176 (84.6%) suffered from the persistence of LBP. Low social support at baseline was significantly related to persistent LBP one year later. The incidence of persistent LBP was 89.9% and 80.0% among those with and without low social support at baseline, respectively. The adjusted odds ratio (95% confidence interval) of low social support at baseline for the persistence of LBP was 2.43 (1.01–5.87). Of 150 who were without LBP at baseline and provided information on LBP one year later, 45 (30.0%) suffered from the onset of LBP. None of the psychosocial work characteristics showed significant relationships with the onset of LBP one year later. Conclusion Low social support was related to the persistence, but not to the onset of LBP in a prospective cohort analysis among daycare workers in Japan. High job strain, ERI, or overcommitment did not show a significant prospective effect on LBP.

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Section: Discussionmentioning

confidence: 84%

Psychosocial work characteristics and low back pain in daycare (nursery) workers in Japan: a prospective cohort study

Shi

Aoshima

Iida

et al. 2022

BMC Musculoskelet Disord

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“…Pain in shoulder (28%), leg (25%), back (23.1%) and neck (22.2%) was most commonly found to be associated with high CSI scores. The previous studies have also claimed a high prevalence of CS in subjects of chronic low back pain 7,9,16 , neck pain 7, 12 15 , extremities pain 15 and knee pain 22 . These differences can be attributed to variation of various factors like different lifestyle, structural, psychosocial and neurophysiological factors 16 .…”

Section: Discussionmentioning

confidence: 87%

“…CS provides evidence based explanation for such cases and is defined as increased responsiveness of nociceptive neurons in the central nervous system which results in hypersensitivity to stimuli and an increased pain response 8 . It is oftenly associated with mechanical hyperalgesia and allodynia in patients with chronic pain conditions 9 .…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Central Sensitization in Chronic Musculoskeletal Pain Disorders

Nitin Pruthi,

Pankajpreet Singh,

Supreet Bindra

2023

IJPOT

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Chronic musculoskeletal pain (CMP) is a leading cause of work absenteeism and increased costs for employers and the health care systems. It may emanate from activation of peripheral nociceptors due to tissue damage, but when the perception of pain persists beyond the expected time for tissue healing, it has become chronic. Central Sensitization (CS) is an important mechanism involved in chronic pain conditions causing amplified responses to noxious and innocuous inputs. Despite the association of CS in Chronic musculoskeletal pain disorders (CMPDs), the evidence regarding prevalence of CS in CMPDs is lacking.Methodology: A descriptive study to document prevalence of CS in CMPDs was conducted among 190 participants with age group 18-65 years. The Central Sensitization Inventory (CSI) was used to determine severity of CS in chronic pain. Results and Conclusions:The mean CSI score for the whole sample was 26.28±13.32 and the prevalence of CS was highest among participants with shoulder pain (28.6%) followed by leg pain (25%) and back pain (23.1%). In clinical practice, modification of life style factors and improving quality of life in patients with chronic musculoskeletal pain could be instrumental in mediating management strategies of CS in addition to pharmacological treatment.

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“…Participants completed an interviewer-administered questionnaire that included information on age, sex, the presence of chronic LBP (cLBP), LBP intensity, and health-related quality of life (QOL), including the EuroQOL 5-Dimension (EQ-5D), EuroQOL Visual Analogue Scale (EQ-VAS), and Oswestry Disability Index (ODI), as previously reported [ 10 ]. LBP intensity was measured using an 11-grade pain intensity numerical rating scale (NRS) [ 11 ] ( S1 File ).…”

Section: Methodsmentioning

confidence: 99%

Novel elemental grading system for radiographic lumbar spondylosis in a population based-cohort study of a Japanese mountain village

et al. 2022

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Purpose Lumbar radiography is a primary screening tool for lumbar spondylosis (LS). Kellgren-Lawrence (KL) classification is widely used to evaluate LS; however, it cannot individually evaluate each radiographic feature. The purpose of this study was to 1) evaluate radiographic LS using a novel elemental grading system and 2) investigate the relationship between the grades of radiographic LS and low back pain (LBP) in a population-based cohort study. Methods A total of 260 (75 men, 185 women; mean age, 71.5 ± 8.7 years) participants were included in this study. Participants were divided into two groups according to the presence of LBP (LBP- and LBP+ groups). Radiographic features, including osteophyte (OP), disc height narrowing (DHN), vertebral sclerosis (VS), and spondylolisthesis (SL), were classified between grades of 0–2 grades according to the extent of radiographic changes. The sum of grades at each intervertebral level was designated as the intervertebral grade (IG). Results Intra- and inter-observer reliability (kappa coefficient) of OP, DHN, VS, and SL were 0.82–0.92. OP, DHN, VS, and IG grades were significantly higher in the LBP+ group than in the LBP- group. There were no significant differences in KL grades between the LBP- and LBP+ groups. Logistic regression analysis demonstrated that VS grade was a significant independent factor associated with LBP. Conclusion The novel elemental grading system of LS would reflect LBP more accurately than the KL classification by individually evaluating each radiographic feature.

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Central Sensitization in Chronic Low Back Pain: A Population-Based Study of a Japanese Mountain Village

Cited by 12 publications

References 44 publications

Psychosocial work characteristics and low back pain in daycare (nursery) workers in Japan: a prospective cohort study

Psychosocial work characteristics and low back pain in daycare (nursery) workers in Japan: a prospective cohort study

Prevalence of Central Sensitization in Chronic Musculoskeletal Pain Disorders

Novel elemental grading system for radiographic lumbar spondylosis in a population based-cohort study of a Japanese mountain village

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