Central Retinal Vein Occlusion

Hayreh, Sohan Singh

doi:10.1007/978-3-319-12781-1_24

Cited by 4 publications

(3 citation statements)

References 362 publications

(288 reference statements)

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“…Central retinal vein occlusion (CRVO) was classified as ischaemic if there was presence of RAPD with extensive retinal haemorrhage and marked visual impairment or development of profound nonperfusion and/or neovascular sequelae attributable to CRVO. Conversion from non‐ischaemic to ischaemic CRVO was defined as recurrence of vascular occlusion event demonstrating markedly increased retinal haemorrhage accompanied by decreased visual acuity and development of RAPD, and consequent enlargement of nonperfusion area larger than 75 disc areas on FA (Hayreh 2015). To avoid errors from decreased vision and destructed retinal structures, retinal haemorrhages or macular oedema at acute phase of CRVO, all the ophthalmic examinations were re‐evaluated at 3 months after the onset of CRVO.…”

Section: Methodsmentioning

confidence: 99%

Glaucoma as a prognostic factor of central retinal vein occlusion: visual and anatomical outcomes and occurrence of ischaemic central retinal vein occlusion

Kim

Shin

Park

et al. 2020

Acta Ophthalmologica

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Purpose To compare the functional and anatomical outcomes of central retinal vein occlusion (CRVO) according to the presence of glaucoma before the onset of CRVO, and to assess whether pre‐existing glaucoma affects the prognosis of CRVO in terms of development and conversion to ischaemic CRVO. Methods In this retrospective cohort study, patients with treatment‐naïve CRVO were enrolled between December 2009 and February 2019. The patients were classified into two groups according to the presence of pre‐existing primary open‐angle glaucoma at CRVO diagnosis. We reviewed medical records regarding basic demographics, ocular characteristics and treatments. The effects of pre‐existing glaucoma on the occurrence of ischaemic CRVO were also investigated using Cox proportional hazard models. Results Of 166 eyes from 166 patients, 26 (15.7%) had pre‐existing glaucoma. The pre‐existing glaucoma group revealed significantly older (69.4 ± 13.3 versus 56.5 ± 15.9) and lower BCVA at baseline (1.06 ± 0.75 versus 0.64 ± 0.58, logMAR) and final visits (1.56 ± 1.35 versus 0.64 ± 0.48, logMAR) (all p < 0.05) than non‐glaucomatous group. In terms of perfusion status of CRVO, the glaucoma group showed higher incidence of ischaemic CRVO (30.8% versus 5.3%, p = 0.052) at initial and last visits as well as more disorganization of retinal inner layers (DRIL) at 3 months (76.0% versus 49.6%, p = 0.015). Pre‐existing glaucoma (hazard ratio (HR) = 2.141, p = 0.014), lower vision at baseline (HR = 2.071, p = 0.001) and DRIL at 3 months (HR = 2.905, p = 0.011) were significant risk factors for the occurrence of ischaemic CRVO. Conclusion In patients with CRVO, pre‐existing glaucoma was associated with poorer visual and anatomical outcomes, and played as a significant risk factor for the development and conversion to ischaemic CRVO with lower vision and presence of DRIL at early phase of CRVO.

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Section: Methodsmentioning

confidence: 99%

Glaucoma as a prognostic factor of central retinal vein occlusion: visual and anatomical outcomes and occurrence of ischaemic central retinal vein occlusion

Kim

Shin

Park

et al. 2020

Acta Ophthalmologica

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“…There are two types of vein occlusion, ischemic and non ischemic . 1 The main complications of CRVO are cystoid macular edema (ME), ocular neovascularization and vitreous hemorrhage. 2 Cystoid macular edema may lead to severe visual loss the treatment of which depends mainly on anti-VEGF injections.…”

Section: Introductionmentioning

confidence: 99%

Vitrectomy with Internal Limiting Membrane Peeling with Intravitreal Ranibizumab Injection for Patients with Central retinal Vein Occlusion with Combined Epiretinal Membrane

Ali

2021

Al-Azhar International Medical Journal

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Background: Central retinal vein occlusion (CRVO) is one of the most common causes of visual loss in general population especially in middle age and elderly people. Aim of The Work:To assess the role of vitrectomy with internal limiting membrane (ILM) peeling with intravitreal ranibizumab injection for patients with CRVO with combined epiretinal membrane (ERM). Patient and Methods:The study was conducted on eleven patients with CRVO with coexisting ERM. Best corrected visual acuity (BCVA) converted into logMAR, fundus Fluorescein angiography and optical coherence tomography (OCT) assessing central macular thickness (CMT) were done. All patients had undergone vitrectomy with ILM peeling with intravitreal injection of ranibiaumab (0.5 mg/0.05 ml). Postoperatively, the patients were examined 1 week and 1 month for BCVA in logMAR and full ophthalmic examination. Also, OCT was done one month postoperatively. Results: There was a significant decrease in one week (1.064±0.258) and four weeks (0.718±0.316) postoperative BCVA in log Mar than preoperative BCVA (1.245±0.221). Also, there was a significant reduction in the four-week postoperative CMT (357.73±133.094) than preoperative CMT (497.27±225.420) ( =0.003). Conclusion:Vitrectomy combined with ILM peeling with intravitreal ranibizumab injection showed anatomical efficacy for macular edema (ME) in eyes with CRVO associated with ERM. Also, BCVA improved significantly concurrently.

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“…Заболевание носит односторонний характер, однако в 7% случаев в течение 5 лет возможно развитие заболевания на парном глазу [4,7]. В настоящее время основные механизмы патогенеза тромбообразования достаточно хорошо изучены.…”

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Changes in hemostasis-related parameters of blood and lacrimal fluid in patients with retinal vein occlusion

Yarovaya

Tsikhonchuk

et al. 2016

Vestn. oftal'mol.

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High prevalence of retinal vein occlusion in young people as well as treatment complexity and inadequate control of hemostatic parameters of blood and lacrimal fluid determine the significance of relevant research in patients with retinal vascular pathology. The data thus obtained may be useful for disease prognosis, severity evaluation and therapy control. This review is aimed to study hemostasis-related parameters of blood and lacrimal fluid in such patients.

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Central Retinal Vein Occlusion

Abstract: © Springer International Publishing Switzerland 2015 176 (26.1 %) 107 (24.3 %) 27 (25.0 %) 35 (35.4 %) 7 (25.9 %) Reproduced from Hayreh et al. [ 156 ] Association of Ocular Hypertension and Glaucoma with CRVO and Hemi-CRVO (HCRVO) Seasonal Variations in the Onset of CRVO

Cited by 4 publications

References 362 publications

Glaucoma as a prognostic factor of central retinal vein occlusion: visual and anatomical outcomes and occurrence of ischaemic central retinal vein occlusion

Glaucoma as a prognostic factor of central retinal vein occlusion: visual and anatomical outcomes and occurrence of ischaemic central retinal vein occlusion

Vitrectomy with Internal Limiting Membrane Peeling with Intravitreal Ranibizumab Injection for Patients with Central retinal Vein Occlusion with Combined Epiretinal Membrane

Changes in hemostasis-related parameters of blood and lacrimal fluid in patients with retinal vein occlusion

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