Central odontogenic fibroma of the maxilla

Abstract

Central odontogenic fibroma (COF) is an uncommon tumor that accounts for 0.1% of all odontogenic tumors; it has been defined as a benign neoplasm of the jaw. Clinically, the lesion grows slowly and leads to cortical expansion. Radiologically, the most common finding is multilocular radiolucency. The lesions are associated with the crown of an unerupted molar, premolar, or incisor tooth and in some cases, with root resorption or displacement. Histologically, the lesion is characterized by mature collagen fibers and numerous fibroblasts. COF responds well to surgical enucleation with no tendency for malignancy or recurrence. We report a case of a 15-year-old female patient presented with painless swelling of the left side of the maxilla since her childhood. Radiographs revealed an expanding ill-defined radiolucency with a displacement of the adjacent tooth. The impacted tooth was pushed posteriorly. The lesion was removed surgically. There were no postoperative complications.

Central Odontogenic Fibroma: characteristics and management

“…They were absent in 74.8% of cases [11,24,36,47,50,[57][58][59][60][61][62][63][64][65]. Facial asymmetry was observed in 23.7% of cases [5,[7][8][9][12][13][14][15][16][17][18][20][21][22]25,26,31,33,40,58,60,63,[66][67][68][69][70][71][72][73][74]. This facial asymmetry was isolated in 20.7% of cases and associated with other extraoral clinical signs in 3% of cases (lymphadenopathy in 1.5% of cases [12,66], trismus in 0.7% [33] and paraesthesia in 0.7% [73] depression could also be associated in 2.2% of cases…”

“…More rarely, COF presented itself in dental signs, as they were found in only 18.4% of cases. Thereby, delayed tooth eruption was noted in 9.6% of cases [12,16,20,35,44,46,48,52,57,58,66,80], mobility in 8.1% of cases [10,12,[30][31][32]38,42,79,81,82] and exceptionally pulp necrosis in 0.7% of cases [50].…”

“…The association of COF with impacted tooth was relatively common (28.9% of cases). It might be canine or molar [5,12,15,16,18,20,25,[35][36][37]40,43,44,46,48,50,51,[57][58][59][60]62,66,67,69,72,77,78,80,83]. Finally, cortical bone perforations were reported in 16.3% of cases [5,10,12,13,16,18,22,28,33,43,47,50,54,56,67,69,71,72,77,81,83,…”

“…When COF was associated with an impacted tooth, differential diagnoses included dentigerous cyst, desmoplastic fibroma, ameloblastoma, odontogenic keratocyst, and ameloblastic fibroma [5,12,15,16,18,25,36,37,40,44,46,51,[57][58][59][60]62,66,67,69,72,77,78,83]. On the contrary, when COF was not associated with a tooth, a wide range of odontogenic tumours could be evoked such as odontogenic myxoma [9,10,14,21,23,24,29,30,34,54,59,65,67,68,76,77].…”

Central Odontogenic Fibroma, its Treatment and its Recurrence: A Systematic Review

“…However, there are special cases in which resections are necessary due to the extension of the tumor that compromises the bony structures, thus not allowing a conservative treatment; such El-Harti K, et al, [58] * n = number of patients n = number of patients treatments include mandibulectomy, hemimandibulectomy, resection and reconstruction with bone grafts or free flaps [42,[54][55][56]. As the technology and new treatments are discovered, various methods have been implemented for treating this tumor and to lower its recurrence, such as laser treatment described by Monteiro LS [57], or the use of liquid nitrogen as described by Garcia-Cano et al, [63].…”