2006
DOI: 10.1016/j.jaci.2006.08.011
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Central obesity is associated with nonatopic but not atopic asthma in a representative population sample

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Cited by 107 publications
(107 citation statements)
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References 55 publications
(52 reference statements)
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“…This has been commented on elsewhere [23]. A number of other mechanisms have been suggested to contribute to a rise in asthma symptoms, including weight gain and lifestyle factors, which result in reduced cardiovascular fitness and breathlessness [5,8,25,26]. However, these possibilities are not supported by the lack of change from 1981 to 2005-2007 in shortness of breath or AHR.…”
Section: Resultsmentioning
confidence: 99%
“…This has been commented on elsewhere [23]. A number of other mechanisms have been suggested to contribute to a rise in asthma symptoms, including weight gain and lifestyle factors, which result in reduced cardiovascular fitness and breathlessness [5,8,25,26]. However, these possibilities are not supported by the lack of change from 1981 to 2005-2007 in shortness of breath or AHR.…”
Section: Resultsmentioning
confidence: 99%
“…A few studies have investigated the association of waist circumference and asthma [11][12][13][14][15][16][17], and considerably fewer studies have taken BMI into consideration in the association [15,17]. Most of these studies are cross-sectional in nature, subject to reverse causality, and their observed association of waist circumference with asthma may be confounded by BMI [11][12][13][14][15][16]. In the Nurses' Health Study of 85,911 females, waist circumference was not found to be associated with incident asthma after adjustment for BMI [17].…”
Section: Discussionmentioning
confidence: 99%
“…Abdominal subcutaneous and visceral fat deposits as measured by waist circumference may be metabolically different from other body fat, indicating a separate risk for common medical complications from peripheral fatness measured by BMI [8]. Only a few studies have investigated the association between abdominal obesity and asthma, most of which have been cross-sectional and have not taken BMI into consideration [11][12][13][14][15][16][17]. BMI and waist circumference are highly correlated [4]; to study the association between waist circumference and asthma, BMI should be considered.…”
mentioning
confidence: 99%
“…The findings have been concordant in adolescents and adults [5]. One study also reported a positive relationship between hip/waist ratio and asthma incidence [6], and another found an inverse relationship between body height and asthma incidence [7]. Furthermore, one study found the body mass index (BMI)-asthma relationship only in nonatopic disease [6].…”
mentioning
confidence: 95%
“…One study also reported a positive relationship between hip/waist ratio and asthma incidence [6], and another found an inverse relationship between body height and asthma incidence [7]. Furthermore, one study found the body mass index (BMI)-asthma relationship only in nonatopic disease [6]. A recent meta-analysis of prospective studies concluded that asthma incidence increased by 50% in overweight/obese individuals [8].…”
mentioning
confidence: 99%