“…We create a contusive injury on the spinal cord in our ovine model using a modified version of a standard weight-drop technique 28,29 which was first employed in sheep by Yeo and colleagues [30][31][32][33][34] and used recently in swine. 25 The configuration of our custom apparatus, designed to achieve a repeatable level of incomplete SCI, is shown in Figure 1.…”
The ovine model is workable as a large animal surrogate suitable for translational studies of novel SCS therapies aimed at relieving spasticity in patients with SCI.
“…We create a contusive injury on the spinal cord in our ovine model using a modified version of a standard weight-drop technique 28,29 which was first employed in sheep by Yeo and colleagues [30][31][32][33][34] and used recently in swine. 25 The configuration of our custom apparatus, designed to achieve a repeatable level of incomplete SCI, is shown in Figure 1.…”
The ovine model is workable as a large animal surrogate suitable for translational studies of novel SCS therapies aimed at relieving spasticity in patients with SCI.
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