Central motor conduction by different stimulation techniques: A study in Friedreich's ataxia patients

Perretti, A.; Caruso, Giuseppe; Lanzillo, B.; Madonna, Claudio; Filla, A.; Santoro, Lucio

doi:10.1016/0013-4694(90)92146-n

Cited by 6 publications

(1 citation statement)

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“…These results agree with those of Claus et al [6] and with our previous data obtained by means of magnetic stimulation [21]. Only one patient, who was at an early stage of disease, showed normal MEP findings.…”

Section: Discussionsupporting

confidence: 93%

Evoked potentials in inherited ataxias: A multimodal electrophysiological study

et al. 1994

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A multimodal electrophysiological study, including median nerve somatosensory evoked potentials (SSEPs), motor cortical stimulation (CS) and brainstem evoked potentials (BAEPs), was performed on 34 patients with hereditary ataxias (HAs): 15 with Friedreich's disease (FD), 10 with early onset cerebellar ataxia (EOCA), and 9 with autosomal dominant cerebellar ataxia (ADCA). A higher incidence of abnormal central motor conduction was observed in FD than in EOCA patients, but was never observed in ADCA. A relationship between central motor conduction abnormalities and disease duration and clinical impairment was found only in FD patients. All FD patients showed severe impairment of the SSEPs that was not related to disease duration. In EOCA patients, less frequent and more variable SSEP abnormalities were observed. The lowest incidence of central SSEP abnormalities was observed in ADCA. The BAEP findings in all 3 groups of patients (but particularly those with EOCA) suggest prevalent brainstem damage.

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Section: Discussionsupporting

confidence: 93%