Central line bundle including split-septum device and single-use prefilled flushing syringes to prevent port-associated bloodstream infections: A cost and resource-utilization analysis

Abstract

Background: Central line bundle programs were found to be effective in decreasing central line-associated bloodstream infection rates in pediatric cancer patients with ports. However, cost-effectiveness studies of central line bundle programs in pediatric cancer patients are limited, and most available data are from intensive care unit or adult studies. Methods: In this cross-sectional study spanning 6 years, comprehensive assessment of total health care costs attributable to CLABSI's associated with ports between two periods. Results: This cross-sectional study was carried out in the pediatric hematology-oncology ward of Dr. Behçet Uz Children's Hospital from 1 August 2011 to 31 July 2017. The CLABSI rates decreased significantly from 8.31 CLABSIs to 3.04 per 1000 central line days (p<0.001). In the prebundle period, total attributable costs spent for of patients with CLABSI were $130661, and in the bundle period, total attributable costs spent for patients with CLABSI were $116579. Within bundle implantation, 71 potential CLABSI were prevented, which saved an additional $208977. Conclusion: Our study shows that central line bundles decreases not only the CLABSI rate but also decreases attributable costs due to CLABSI. Expenses spent for bundle elements, were covered by savings by preventing CLABSI with higher costs

Prolonged flushing and locking interval for totally implantable vascular access device: A systematic review and meta-analysis

“…5 Flushing is the most important measure to reduce complications especially catheter occlusions and infections. 28 Although the manufacturers recommend flushing ports every 4 weeks, there is no good evidence in the frequency of catheter flushing. 18…”

Correction to: Central line bundle including split-septum device and single-use prefilled flushing syringes to prevent port-associated bloodstream infections: a cost and resource-utilization analysis

“…Following publication of the original article [1], the authors would like to exchange the Table 1's caption and Table 2's caption. The correct ones are shown below.…”