Central giant cell granuloma: A case report and review

Buduru, Krishnaveni; Podduturi, Sanjay Reddy; Vankudoth, Dal Singh; Prakash, Jacob

doi:10.4103/jiaomr.jiaomr_100_15

Cited by 5 publications

(7 citation statements)

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“…CGCG is frequently reported in females less than 30 years of age with anterior mandible as the most commonly affected site. 4 However, our case was a 35 years old female with the lesion in posterior mandible. Medical treatment of this lesion includes intralesional corticosteroid injections for 6 weeks, subcutaneous calcitonin injections for 1 year, interferon alpha-2b subcutaneous injections or combination.…”

Section: Discussionmentioning

confidence: 76%

“…World health organization classified central giant cell granuloma in 2005 as the rarely aggressive lesion of jaw that may be asymptomatic or present with pain, paresthesia and bone perforation. 4 Jaffee (1953) considered this lesion as reparative reaction of bone. 5,6 Cossío et al suggested that trauma is the main cause of CGCG.…”

Section: Discussionmentioning

confidence: 99%

“…8,9 Surgical treatment options include curettage alone (with more chances of recurrence) or curettage with enucleation, resection and peripheral ostectomy as the best treatment option. 4 Intraoperative complications of these surgical procedures include damage to adjacent teeth and nerves, bleeding, and tearing of lesion lining. Postoperative complications include infection, wound dehiscence, graft failure, facial asymmetry, and recurrence.…”

Section: Discussionmentioning

confidence: 99%

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Aggressive Central Giant Cell Granuloma: A Case Report

Hammad¹,

Ayoub

Tariq

et al. 2020

JIMDC

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Central giant cell granuloma (CGCG) is a benign non odontogenic lesion of jaw that may show aggressive behavior. It is classified as aggressive and non-aggressive lesion on the basis of biological behavior and radiographic features. Central giant cell lesion is more frequent in children and young adult before the age of 30 years with female predilection, with characteristic radiological and histopathological features. Here we present a case of a 35 years old female with clinical and radiological diagnosis of central giant cell lesion in posterior mandible confirmed by histopathology. A surgical approach with regular follow up is the treatment of choice in most of the cases. Key Words: Calcitonin, Corticosteroid, Curettage, Enucleation, Giant cell lesion

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Section: Discussionmentioning

confidence: 76%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Aggressive Central Giant Cell Granuloma: A Case Report

Hammad¹,

Ayoub

Tariq

et al. 2020

JIMDC

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“…Larger lesions cause loosening or displacement of teeth, divergence of roots, and root resorption, but the teeth in the affected region are always vital. [ 5 6 ] Radiographic appearances of large lesions appear multilocular but are unilocular with a lobular margin. [ 7 ] It is often difficult to differentiate between central giant cell granuloma and brown tumor of hyperparathyroidism on the basis of clinical, radiological, and histopathological features.…”

Section: Discussionmentioning

confidence: 99%

An Intraosseous Giant Cell Granuloma

Pavan

Subramani

Pandian

et al. 2021

Journal of Pharmacy and Bioallied Sciences

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The giant cell granuloma is an identical reactive lesion which is mostly progressive in nature. The clinical behavior of these lesions varies from indolent to aggressive variant. The central form of giant cell granuloma involves the craniofacial bone, followed by long bones of hands and feet. These lesions are usually asymptomatic lesions and are discovered incidentally during routine radiographic examination. Radiograph features reveal multilocular jaw lesions, generally anterior to the first molar regions. Histologically, the lesion shows proliferating spindle-shaped stromal cells in a fibrovascular connective tissue stroma, which characteristically contains multiple multinucleated giant cells. Hemorrhage and hemosiderin pigmentations are often seen in tumor. Central giant cell granuloma is often confused with giant cell tumor of bone histologically. Here, we report a young male who was found to have large central giant cell granuloma in the anterior part of the mandible. The surgical treatment approach of central giant cell granuloma is discussed in this article.

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“…10 The lesion has been reported to be confined to the tooth bearing area of the jaw and is more common in anterior portion of the mandibular body. 11 CGCG presents as a painless clinical expansion that may have a short ascendancy. The expanded lesion may appear blue because of its cortical and mucosal thinning and internal vascularity.…”

Section: Discussionmentioning

confidence: 99%

Management of central giant cell granuloma: A case series

Wadde¹,

Landge²,

Rathod³

et al. 2020

JOOO

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Central giant cell granuloma (CGCG) is an uncommon, benign, and proliferative lesion of the jaw with an unknown aetiology, was first described by Jaffe in 1953.The lesion is found predominantly in children and young adults, with more than 60% of all cases occurring before the age of 30 years. The female: male ratio is 2:1. Lesions are more common in the anterior region of the jaws, and mandibular lesions frequently extend across the midline. CGCG can be difficult to diagnose from other lesion of oral cavity like Hyperparathyroid tumour, Ameloblastoma, Odontogenic myxoma, Haemangioma, Cherubism, Central odontogenic fibroma, Aneurysmal bone cyst, Traumatic bone cyst. Numerous treatment modalities given in literature from non-surgical to surgical. This paper intends to focus on diagnosis, clinical presentation and different management options of CGCG. So our aim was to evaluate the response of treatment of CGCG to intralesional injection.

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Central giant cell granuloma: A case report and review

Cited by 5 publications

References 1 publication

Aggressive Central Giant Cell Granuloma: A Case Report

Aggressive Central Giant Cell Granuloma: A Case Report

An Intraosseous Giant Cell Granuloma

Management of central giant cell granuloma: A case series

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