2023
DOI: 10.22159/ijap.2023v15i1.46289
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Central Composite Face-Centered Design-Based Optimisation, Development and Characterisation of Favipiravir-Loaded Plga Nanoparticles

Abstract: Objective: The objective of this study is to fabricate favipiravir-loaded PLGA nanoparticulate systems that can increase the solubility along with the sustained release of favipiravir. Methods: The favipiravir-loaded Poly (D, L-lactic-co-glycolide) (PLGA) nanoparticulate systems were prepared by the nanoprecipitation method. A 3-factor, 2-level central composite face-centered design was employed to study the effect of formulation variables having a concentration of PLGA, polyvinyl alcohol (PVA) and stirring ra… Show more

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