Central Chirality and Axial Chirality Recognition of the Enantioselective Antibodies to Herbicide Metolachlor
Xing Shen,
Yan Zhang,
JingJing Xu
et al.
Abstract:Enantioselective antibodies have emerged as efficient tools in the field of chiral chemical detection and separation. However, it is complicated to obtain a highly stereoselective antibody due to the unclear recognition mechanism. In this study, the hapten of metolachlor was synthesized and enantio-separated. The absolute configuration of the four haptens obtained was identified by the computed and experimental electronic circular dichroism comparison. Five polyclonal antibodies against the Rac-metolachlor and… Show more
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