Central blood pressure and pulse wave velocity in young and middle-aged Japanese adults with isolated systolic hypertension

Nakagomi, Atsushi; Imazeki, Fumio; Nishimura, Motoi; Sawabe, Yuji; Matsushita, Hiroshi; Murata, Akitoshi; Watase, Mariko; Okada, Sho; Kobayashi, Yoshio

doi:10.1038/s41440-019-0364-x

Cited by 7 publications

(16 citation statements)

References 23 publications

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“…Our study demonstrated that a higher BP is a contributing factor to arterial stiffness, even when it is within the normal range, and the effect of SBP on baPWV was more prominent than that of PP. The association between BP and arterial stiffness has been debated in various studies [ 11 , 13 , 26 , 27 , 31 , 32 ]. Longitudinal studies have shown that a large PP in childhood plays a role in the development of subclinical vascular damage in adulthood, and the early prevention of a large PP can reduce the future risk of cardiovascular disease [ 14 ].…”

Section: Discussionmentioning

confidence: 99%

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Factors Associated with Brachial-Ankle Pulse Wave Velocity in an Apparently Healthy Chinese Population

Chen

Liu

Jia

et al. 2020

BioMed Research International

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Purpose. To investigate the factors influencing brachial-ankle pulse wave velocity (baPWV) in an apparently healthy Chinese population, especially the associations between baPWV and indices of blood pressure (BP). Methods. A total of 1123 participants with no history of hypertension were enrolled in this study, and the baPWV and BP of all four limbs were measured along with other covariates. Correlation analyses and multivariate linear regression models were used to identify factors associated with baPWV. Results. A total of 1123 participants (male 43.3%, mean age: 58.4±13.9 years) were included. The average baPWV was 14.87±3.21 m/s, and no difference was found between the sexes. Age was positively correlated with baPWV (r=0.65, p<0.01), especially in females (r=0.71 versus 0.56 in males). The correlation coefficient between age and baPWV increased markedly after the age of 65 years. In addition, the resting heart rate (RHR), waist-hip ratio, glomerular filtration rate, and plasma glucose level were significantly correlated with baPWV (r=0.25, 0.22, -0.43, and 0.25, respectively; p<0.01). BP parameters were highly positively correlated with baPWV, especially systolic BP (SBP) and pulse pressure (PP). Multivariate regression revealed that age, BP parameters, and RHR were independently correlated with baPWV (p<0.01) after adjusting for confounding factors. The standardized coefficients of SBP were greater than those of PP, followed by diastolic BP (DBP). Conclusion. BaPWV increased with age, especially after 65 years. Age, BP, and RHR were independent factors associated with baPWV. The effect of SBP on baPWV was more prominent than that of PP.

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Section: Discussionmentioning

confidence: 99%

“…Most studies on baPWV-associated factors have focused on patients with hypertension and the other diseases mentioned above [11][12][13][14], but arterial stiffness is not confined to patients with hypertension. In nonhypertensive individuals, it is not clear whether blood pressure (BP) has an effect on baPWV.…”

Section: Introductionmentioning

confidence: 99%

Factors Associated with Brachial-Ankle Pulse Wave Velocity in an Apparently Healthy Chinese Population

Chen

Liu

Jia

et al. 2020

BioMed Research International

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“…12 In the male Japanese workers and University students, the ISH participants had greater body mass index and waist circumference than participants with optimal blood pressure. 26 In the ENIGMA study ISH subjects were taller, heavier, had a greater body mass index, and were more likely to be male, when compared with normotensive subjects. 11…”

Section: Clinical Characteristics Of Ish In the Young And Middle-agmentioning

confidence: 99%

“…12 In the male Japanese workers and University students, central SBP in subjects with ISH was higher when compared with subjects with high-normal blood pressure but was lower than that of SDH, but central PP in ISH was higher than that of high-normal blood pressure, IDH and SDH. 26 In the ENIGMA study, subjects 37 The use of different central blood pressure measurement devices apparently may affect the estimation of the prevalence of spurious hypertension.…”

Section: Clinical Characteristics Of Ish In the Young And Middle-agmentioning

confidence: 99%

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Isolated systolic hypertension and central blood pressure: Implications from the national nutrition and health survey in Taiwan

Chuang

Chang

Tsai

et al. 2020

J of Clinical Hypertension

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Isolated systolic hypertension (ISH) is defined as systolic blood pressure (SBP) ≥140 mmHg and diastolic blood pressure (DBP)<90 mmHg. 1 The prevalence of ISH increases with age along with the decreasing DBP and the widening pulse pressure (PP). ISH is commonly viewed as the manifestation of vascular aging and is conceivably the most common subtype of hypertension in the elderly population. 2-4 The elderly with ISH have a significantly higher risk of cardiovascular diseases 5,6 and benefit substantially from antihypertensive therapy. 7-9

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Role of arterial stiffness and central hemodynamics in personalized medicine in hypertension

Cheng

Chuang

Sung

et al. 2022

Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease

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Central blood pressure and pulse wave velocity in young and middle-aged Japanese adults with isolated systolic hypertension

Cited by 7 publications

References 23 publications

Factors Associated with Brachial-Ankle Pulse Wave Velocity in an Apparently Healthy Chinese Population

Factors Associated with Brachial-Ankle Pulse Wave Velocity in an Apparently Healthy Chinese Population

Isolated systolic hypertension and central blood pressure: Implications from the national nutrition and health survey in Taiwan

Role of arterial stiffness and central hemodynamics in personalized medicine in hypertension

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