“…In the old world (southern Europe, the Middle East, southwest Asia, and Africa), approximately 20 different Leishmania species are responsible for the transmission of CL, including L tropica, L. major, L. aethiopica, L. infantum, and L. donovani , with L. major representing the most common causative organism [ 7 ]. In the new world (from the southern United States through Latin America to South America), L. mexicana , L. venezuelensis , L. amazonensis , L. braziliensis , L. panamensis , L. guyanensis, and L. peruviana are the primary causal species of CL [ 8 , 9 ]. In Colombia, the overall leishmaniasis incident rate is 26.2 cases per 100,000 population (including 98.6% of the cases related to CL), and in Brazil, autochthonous cases of CL have been reported in all states.…”