Abstract:The aim of the study was to verify the effect of central angiotensin II AT2 receptor blockade in thermoregulatory responses during exercise in rats. Internal (Tb) and skin tail (Ttail) temperatures were measured in Wistar rats while they were running until fatigue (18 m.min‐¹, 5% inclination) after intracerebroventricular injection of 2µL of PD 123319 (PD; AT2 angiotensin II receptor antagonist; 10 µg) or 0.15 M NaCl (SAL) (n=7/each). Total time of exercise until fatigue (TTE) and workload (W) were determined.… Show more
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