Central and Peripheral Neural Interfaces for Control of Upper Limb Actuators for Motor Rehabilitation After Stroke: Technical and Clinical Considerations

Irastorza-Landa, Nerea; Sarasola-Sanz, Andrea; Bibian, Carlos; Ray, Andreas M.; Insausti-Delgado, Ainhoa; Helmhold, Florian; Mahmoud, Wala; Ortego-Isasa, Iñaki; López‐Larraz, Eduardo; Ramos‐Murguialday, Ander

doi:10.1007/978-981-15-2848-4_120-1

Cited by 1 publication

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“…Concluding, cortico-muscular interfaces that estimate source related CMC might have a greater potential for reinforcing efferent pathways from cortical motor structures to the targeted paralyzed muscles and have therefore been suggested as a promising approach for stroke motor rehabilitation (Irastorza-Landa et al, 2022 ). Furthermore, despite the promising preliminary results presented in this section, further work evaluating the changes in CMC levels in larger stroke patient cohorts enrolled in NI related therapy is needed to demonstrate a direct relationship with gained motor functions, hence, more controlled clinical trials are needed to test neuro-muscular interfaces in stroke survivors.…”

Section: Biotargets For Rehabilitative Neural Interfacesmentioning

confidence: 99%

Challenges of neural interfaces for stroke motor rehabilitation

Vidaurre,

Irastorza-Landa,

Sarasola-Sanz

et al. 2023

Front. Hum. Neurosci.

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More than 85% of stroke survivors suffer from different degrees of disability for the rest of their lives. They will require support that can vary from occasional to full time assistance. These conditions are also associated to an enormous economic impact for their families and health care systems. Current rehabilitation treatments have limited efficacy and their long-term effect is controversial. Here we review different challenges related to the design and development of neural interfaces for rehabilitative purposes. We analyze current bibliographic evidence of the effect of neuro-feedback in functional motor rehabilitation of stroke patients. We highlight the potential of these systems to reconnect brain and muscles. We also describe all aspects that should be taken into account to restore motor control. Our aim with this work is to help researchers designing interfaces that demonstrate and validate neuromodulation strategies to enforce a contingent and functional neural linkage between the central and the peripheral nervous system. We thus give clues to design systems that can improve or/and re-activate neuroplastic mechanisms and open a new recovery window for stroke patients.

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Section: Biotargets For Rehabilitative Neural Interfacesmentioning

confidence: 99%