Centenarians in Europe

Teixeira, Laetitia; Araújo, Lia; Jopp, Daniela S.; Ribeiro, Óscar

doi:10.1016/j.maturitas.2017.08.005

Cited by 42 publications

(20 citation statements)

References 11 publications

(12 reference statements)

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“…Eight out of 10 centenarians are women (Teixeira et al, 2017). In 2016, Koenig and Thayer (2016) published a meta-analysis with 63,612 participants (31,970 females), revealing that: although adult women showed greater mean HR (MHR) than adult male, the female heart is characterized by a dominance of vagal activity (greater HF) and lower standard deviation (SD) of normal-to-normal intervals (SDNN).…”

Section: Introductionmentioning

confidence: 99%

Heart Rate Variability and Exceptional Longevity

et al. 2020

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Section: Introductionmentioning

confidence: 99%

Heart Rate Variability and Exceptional Longevity

et al. 2020

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“…A unique group of aging individuals termed centenarians serves as a healthy aging model, outliving the age of 100, with mostly intact cognition and physical health [1][2][3]. Such exceptionally long-lived individuals (ELLI) are the focus of many studies around the world [4][5][6][7][8][9][10][11][12], and this group is now being studied in Israel as well. Our newly established cohort of ELLI is part of the Israeli Multi-Ethnic Centenarian Study (IMECS), which aims to elucidate the mechanisms of their healthy aging process.…”

Section: Introductionmentioning

confidence: 99%

Exceptionally Long-Lived Individuals (ELLI) Demonstrate Slower Aging Rate Calculated by DNA Methylation Clocks as Possible Modulators for Healthy Longevity

Gutman

Rivkin

Fadida

et al. 2020

IJMS

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Exceptionally long-lived individuals (ELLI) who are the focus of many healthy longevity studies around the globe are now being studied in Israel. The Israeli Multi-Ethnic Centenarian Study (IMECS) cohort is utilized here for assessment of various DNA methylation clocks. Thorough phenotypic characterization and whole blood samples were obtained from ELLI, offspring of ELLI, and controls aged 53–87 with no familial exceptional longevity. DNA methylation was assessed using Illumina MethylationEPIC Beadchip and applied to DNAm age online tool for age and telomere length predictions. Relative telomere length was assessed using qPCR T/S (Telomere/Single copy gene) ratios. ELLI demonstrated juvenile performance in DNAm age clocks and overall methylation measurement, with preserved cognition and relative telomere length. Our findings suggest a favorable DNA methylation profile in ELLI enabling a slower rate of aging in those individuals in comparison to controls. It is possible that DNA methylation is a key modulator of the rate of aging and thus the ELLI DNAm profile promotes healthy longevity.

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“…Individuals born after the year 2000 will likely live ≥100 years [2]. Data from the national census in Europe (Eurostat database) reveal an average of 17.3 centenarians per 100,000 people, with the highest percentage of centenarians in France, Italy, and Greece and 72% of centenarians in Europe live in private households [3]. The factors of centenarians' longevity and health have long been of interest to the scientific community, resulting in a considerable amount of research.…”

Section: Introductionmentioning

confidence: 99%

Oral health of centenarians and supercentenarians

et al. 2020

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There are many studies on the homebound and institutionalized elderly; however, few studies focus on centenarians and supercentenarians, i.e., people aged 100 and 110 years, respectively. Due to the demographic changes, the population of centenarians is set to increase more than that of other age groups. Therefore, this article aims to review the available literature regarding how oral health might display in this age group and highlight aspects necessitating further research. Oral health, oral healthrelated quality of life, saliva, and the oral microbiome were emphasized in this study. Most papers relevant to the research questions were excluded because the mean age of participants was <100 years. Only two papers were found on centenarians' oral health status and saliva and no studies were found focusing on the oral health-related quality of life or oral microbiome. The reviewed studies demonstrate that centenarians presented with good oral mucosal conditions, dental conditions, and general health. The present literature is insufficient to come to a definite conclusion regarding how aging affects the oral health of centenarians and supercentenarians. The limited available research indicates that centenarians display better oral health than other individuals in their respective birth cohorts.

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Centenarians in Europe

Abstract: Centenarian numbers have increased substantially since last available data. The findings will inform specific health promotion policies, the strengthening of current services and the development of innovative care systems.

Cited by 42 publications

References 11 publications

Heart Rate Variability and Exceptional Longevity

Heart Rate Variability and Exceptional Longevity

Exceptionally Long-Lived Individuals (ELLI) Demonstrate Slower Aging Rate Calculated by DNA Methylation Clocks as Possible Modulators for Healthy Longevity

Oral health of centenarians and supercentenarians

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