The formation of the Pamir salient and the Tashkorgan鈥怸arkand River is highly debated with the ages ranging from pre鈥怌enozoic to late Miocene. One approach to resolve these issues is to draw support from the sedimentary record in the surrounding basins. A volcaniclastic sequence, which divides into Lower and Upper Members, was identified in the southwestern Tarim Basin. The Lower Member was transported by dilute streamflows, which likely flowed during or soon after eruptions, while the Upper Member was formed by a syneruptive volcanic debris flow. Chronological, petrologic, and geochemical data consistently indicate that the sequence was derived from the Central Pamir at ~11聽Ma. The ~11 Ma emplacement of the volcaniclastic sequence provides unique constraints for the evolution of the Tashkorgan鈥怸arkand River and the Pamir salient. Provenance data indicate a multistage evolutionary history of the Tashkorgan鈥怸arkand River. The paleo鈥怲ashkorgan River was initially formed in the piedmont of the Pamir marginal range before ~15聽Ma. This river cut back into the Tashkorgan region at ~15聽Ma, after which it has eroded the Central Pamir by ~11聽Ma. The N鈥怱 trending upper reaches of the Tashkorgan River and the Yarkand River were established after ~11聽Ma. The emplacement of the volcanic debris flow, together with regional deformation evidence, indicates limited strike鈥恠lip motion between Pamir and the Tarim at least since ~11聽Ma, which refutes hundreds of kilometers offset between the Pamir and the Tarim after this time and supports an earlier indention of the Pamir salient.