Cemento-ossifying fibroma of the mandible

Abstract

Cemento-ossifying fibromas are rare fibro-osseous benign neoplasms that affect the jaws. They are included in the group of mesodermal odontogenic tumors and commonly present as a progressively growing lesion that might attain enormous size with resultant deformity, if left untreated. A confusion prevails on the terminology, which can only be confirmed by histopathologic evaluation. A case of cemento-ossifying fibroma involving the right mandible is described in a 30 year-old female patient. The clinical, radiographic, histologic features are presented and the various differential diagnosis are discussed.

Central Cemento-Ossifying Fibroma: Clinical Imaging and Histopathological Diagnosis

“…Considering the radiographic characteristics, the reported case shows well-defined mixed lesion. In general, displacements and reabsorption of the tooth roots may appear (Chang et al;Oliveira et al, 2008;El-Mofty;Bala et al), such as in the case reported. Radiographically it is also shown the displacement of the mandibular can alto the mandible base, which are characteristics that suggest a benign lesion.…”

“…The early stage progresses gradually to a mixed lesion as the calcified material settles in the tumor (White & Pharoah; da Silveira et al; Bala et al). Mature lesions may consist of a dense radiopaque mass surrounded by a well-defined radiotransparent line (Titinchi & Morkel, 2016;Bala et al). Considering the radiographic characteristics, the reported case shows well-defined mixed lesion.…”

“…The COF has always given way to some controversy regarding terminology and diagnosis criteria (Soluk-Tekkesin & Wright, 2018) included in the group of odontogenic mesenchymal benign tumors. Its pathogenesis remains unknown, but it can be related to congenital issues during the maturation of the dental tissues, which are able to form cement and bone tissue (Chang et al, 2008;Bala et al, 2017).…”

Multidisciplinary approach in the treatment of ossifying fibroma: Case report

“…It is more common between the third and fourth decade of life in women and occurs predominantly in the mandible. The expansive growth of the lesion can cause tooth displacement, facial asymmetry and functional impairment (Neville, et al, 2016;Bala, et al, 2017).…”

“…Due to the expansion capacity, the fibroma can cause asymmetries, dental displacements, and dysphagia. Since these injuries often lead to major deformities in the stomatognathic segment and can hinder or even prevent proper feeding (de Amorim, et al, 2015;Neville, et al, 2016;Bala, et al, 2017). Thus, nutritional capacity of the patient may be compromised.…”